Results 201 to 210 of about 681,060 (251)

Management of Treatment-Resistant Depression

Psychiatric Clinics of North America, 2012
Given the limitations of evidence for treatment options that are consistently effective for TRD and the possibility that TRD is in fact a form of depression that has a low probability of resolving, how can clinicians help patients with TRD? Perhaps the most important conceptual shift that needs to take place before treatment can be helpful is to accept
Gabor I, Keitner, Abigail K, Mansfield
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Venlafaxine and treatment-resistant depression

Depression and Anxiety, 2000
Treatment-resistant depression (TRD) is an important clinical problem. This paper briefly reviews the definition of TRD and summarizes methodological issues that pertain to treatment research. Recent studies of venlafaxine treatment for TRD also are reviewed.
M E, Thase, E S, Friedman, R H, Howland
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Treatment-resistant depression and suicidality

Journal of Affective Disorders, 2018
Thirty percent of patients with treatment-resistant depression (TRD) attempt suicide at least once during their lifetime. However, it is unclear what the attempted and completed suicide incidences are in TRD patients after initiating a treatment, and whether specific treatments increase or decrease these incidences.We searched PubMed systematically for
Isidoor O. Bergfeld, Mariska Mantione, Martijn Figee, P. Richard Schuurman, Anja Lok, Damiaan Denys   +5 more
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Esketamine Monotherapy in Adults With Treatment-Resistant Depression

JAMA psychiatry
Key Points Question Is esketamine nasal spray used alone (without oral antidepressant) effective in treatment-resistant depression (TRD)? Findings In the efficacy analysis dataset of this double-blind, multicenter, randomized clinical trial of 378 adults
A. Janik, X. Qiu, R. Lane, V. Popova, Wayne C. Drevets, C. Canuso, M. Macaluso, G. Mattingly, R. Shelton, J. Zajecka, Dong-Jing Fu   +10 more
semanticscholar   +1 more source

Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression.

American Journal of Psychiatry, 2020
OBJECTIVE New antidepressant treatments are needed that are effective, rapid acting, safe, and tolerable. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation treatment that has been approved by the U.S.
E. Cole, K. Stimpson, B. Bentzley, M. Gulser, K. Cherian, C. Tischler, R. Nejad, Heather Pankow, Elizabeth Choi, Haley Aaron, F. Espil, Jaspreet Pannu, Xiaoqian Xiao, Dalton Duvio, H. Solvason, Jessica Hawkins, Austin Guerra, Booil Jo, K. Raj, Angela L. Phillips, Fahim Barmak, J. Bishop, J. Coetzee, C. DeBattista, Jennifer Keller, Alan F. Schatzberg, K. Sudheimer, Nolan R. Williams   +27 more
semanticscholar   +1 more source

Treatment-Resistant Depression

Psychotherapy and Psychosomatics, 1998
Our ability to treat depression has improved with the availability of receptor-specific and chemically diverse groups of antidepressants. Even now, most of the short-term studies indicate that about 20% of depressed patients remain resistant to treatment. Therefore, it is important to properly assess the treatment-resistant depressed (TRD) patients and
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Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.

American Journal of Psychiatry, 2021
OBJECTIVE Adolescent depression is prevalent and is associated with significant morbidity and mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its efficacy in pediatric populations is unknown.
J. Dwyer, A. Landeros-Weisenberger, Jessica A. Johnson, Amalia Londoño Tobón, José M. Flores, Madeeha Nasir, Kevin G. Couloures, G. Sanacora, M. Bloch   +8 more
semanticscholar   +1 more source

ECT in Treatment-Resistant Depression

American Journal of Psychiatry, 2012
Electroconvulsive therapy (ECT), which has been in use for 75 years, is an important treatment for severe and treatment-resistant depression. Although it is acknowledged as the most effective acute treatment for severe mood and psychotic disorders, it remains controversial because of misperceptions about its use and lack of familiarity among health ...
Charles H, Kellner, Robert M, Greenberg, James W, Murrough, Ethan O, Bryson, Mimi C, Briggs, Rosa M, Pasculli   +5 more
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Strategies for treatment-resistant depression

Clinical Cornerstone, 1999
Clinical depression is a common disorder with serious implications that is often misdiagnosed or underestimated. More than 50% of suicides are associated with a major depressive disorder, and depression can adversely impact a variety of other medical conditions.
P G, Janicak, B, Martis
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Perspectives for therapy of treatment‐resistant depression

British Journal of Pharmacology, 2021
A high proportion of depressed patients fail to respond to antidepressant drug treatment. Treatment‐resistant depression (TRD) is a major challenge for the psychopharmacology of mood disorders. Only in the past decade have novel treatments, including deep brain stimulation (DBS) and ketamine, been discovered that provide rapid and sometimes prolonged ...
Mariusz Papp, Wiesław Jerzy Cubała, Lukasz Swiecicki, Adrian Newman‐Tancredi, Paul Willner   +4 more
openaire   +2 more sources