Results 1 to 10 of about 39,723 (259)

Experimental Therapeutics in Treatment-Resistant Major Depressive Disorder

Journal of Experimental Pharmacology, 2021
Mandeep Kaur,1 Marsal Sanches2 1Department of Behavioral Medicine, Cone Health, Greensboro, NC, USA; 2UT Health Center of Excellence on Mood Disorders, Faillace Department of Psychiatry & Behavioral Sciences, McGovern Medical School, Houston, TX ...
Kaur M, Sanches M
doaj   +6 more sources

Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder

Neuropsychopharmacology Reports, 2020
Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki, Tomonori Hasegawa, Masatoshi Takeda   +2 more
doaj   +2 more sources

Epidemiology of treatment resistant depression among major depressive disorder patients in Israel

BMC Psychiatry, 2022
Introduction Major depressive disorder (MDD) is one of the most common mental disorders worldwide, estimated to affect 10–15% of the population per year.
Sarah Sharman Moser, Gabriel Chodick, Shulamit Gelerstein, Nava Barit Ben David, Varda Shalev, Orit Stein-Reisner   +5 more
doaj   +3 more sources

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone

Brain and Behavior, 2023
Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive
David M. Kern, Carla M. Canuso, Ella Daly, Jonathan C. Johnson, Dong Jing Fu, Teodora Doherty, Cori Blauer‐Peterson, M. Soledad Cepeda   +7 more
doaj   +2 more sources

Treatment patterns in patients with treatment-resistant depression in Danish patients with major depressive disorder

Journal of Affective Disorders, 2021
To describe treatment patterns in patients with treatment-resistant depression (TRD) and major depressive disorder (MDD) stratified by depression severity and year of diagnosis. Patterns of treatment were also compared to country-specific guidelines.All adults registered first time with a hospital contact due to MDD from 1996 through 2015 were ...
Janne Petersen, Kristoffer Jarlov Jensen, Merete Osler   +2 more
exaly   +4 more sources

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients.

PLoS ONE, 2020
ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang   +7 more
doaj   +2 more sources

Comparison of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder

Sichuan jingshen weisheng, 2021
ObjectiveTo explore the differences of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder， and to examine the relationship between severity of clinical symptoms and cognitive function，
Zheng Chaodun, Chen Yingmei, Tan Jiuwei, Liu Guoxiong, Cai Yinglian, Lan Xiaofeng, Zhou Yanling   +6 more
doaj   +1 more source

Treatment-resistant major depressive disorder and assisted dying [PDF]

Journal of Medical Ethics, 2015
Competent patients suffering from treatment-resistant depressive disorder should be treated no different in the context of assisted dying to other patients suffering from chronic conditions that render their lives permanently not worth living to them.
Schuklenk, Udo, van de Vathorst, Suzanne
openaire   +3 more sources

Increased Serum Levels of Oxytocin in 'Treatment Resistant Depression in Adolescents (TRDIA)' Group. [PDF]

PLoS ONE, 2016
'Treatment-resistant depression' is depression that does not respond to an adequate regimen of evidence-based treatment. Treatment-resistant depression frequently becomes chronic.
Tsuyoshi Sasaki, Kenji Hashimoto, Yasunori Oda, Tamaki Ishima, Madoka Yakita, Tsutomu Kurata, Masaru Kunou, Jumpei Takahashi, Yu Kamata, Atsushi Kimura, Tomihisa Niitsu, Hideki Komatsu, Tadashi Hasegawa, Akihiro Shiina, Tasuku Hashimoto, Nobuhisa Kanahara, Eiji Shimizu, Masaomi Iyo   +17 more
doaj   +1 more source

Resistance or pseudo-resistance?

European Psychiatry, 2022
Introduction Treatment-Resistant Depression continues to represent a great challenge for clinicians. Objectives We investigated patients with history of resistance, assessing prognostic factors, response to treatments, and remission over time ...
R. Zanardi, F. Attanasio, C. De Cesare, V. Fazio, C. Colombo   +4 more
doaj   +1 more source