Results 1 to 10 of about 83,135 (307)

Experimental Therapeutics in Treatment-Resistant Major Depressive Disorder

Journal of Experimental Pharmacology, 2021
Mandeep Kaur,1 Marsal Sanches2 1Department of Behavioral Medicine, Cone Health, Greensboro, NC, USA; 2UT Health Center of Excellence on Mood Disorders, Faillace Department of Psychiatry & Behavioral Sciences, McGovern Medical School, Houston, TX ...
Kaur M, Sanches M
doaj   +5 more sources

Epidemiology of treatment resistant depression among major depressive disorder patients in Israel

BMC Psychiatry, 2022
Introduction Major depressive disorder (MDD) is one of the most common mental disorders worldwide, estimated to affect 10–15% of the population per year.
Sarah Sharman Moser, Gabriel Chodick, Shulamit Gelerstein, Nava Barit Ben David, Varda Shalev, Orit Stein-Reisner   +5 more
doaj   +3 more sources

Case Report: rTMS for recurrent major depressive disorder and generalized anxiety disorder comorbid with atrial fibrillation [PDF]

Frontiers in Psychiatry
This paper examines the utilization of repetitive transcranial magnetic stimulation (rTMS) to treat recurrent Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) in a patient comorbid with atrial fibrillation (AF), a type of common ...
Vipul Reddy, Nadia Frutkin, Nadia Frutkin, Abeer Singh, Abeer Singh, Manya Pappu, Manya Pappu, Khimaya Raval, Khimaya Raval, Mark Odron, Charles Vigilia, Kenneth Blum, Kenneth Blum, Kenneth Blum, Kenneth Blum, Kenneth Blum, Kenneth Blum, David Baron, Keerthy Sunder, Keerthy Sunder, Keerthy Sunder, Keerthy Sunder   +21 more
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Personalizing esketamine treatment in TRD and TRBD: the role of mentalization, cognitive rigidity, psychache, and suicidality [PDF]

Frontiers in Psychiatry
IntroductionTreatment-Resistant Depression (TRD) remains a major challenge in the management of Major Depressive Disorder (MDD). Esketamine, the S-enantiomer of ketamine and a glutamatergic modulator, was approved by the FDA and EMA for TRD in 2019 ...
Miriam Olivola, Miriam Olivola, Filippo Mazzoni, Barbara Tarantino, Alessandro Guffanti, Matteo Marcatili, Monica Macellaro, Monica Macellaro, Monica Macellaro, Nicolaja Girone, Nicolaja Girone, Nicolaja Girone, Vassilis Martiadis, Fabiola Raffone, Tiziano Prodi, Tiziano Prodi, Natascia Brondino, Giovanni Martinotti, Massimo Clerici, Massimo Clerici, Roberta Anniverno, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso   +26 more
doaj   +2 more sources

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients

PLoS ONE, 2020
Objective The economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non–treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J. Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang, Fernando A. Wilson   +8 more
doaj   +2 more sources

Comparison of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder

Sichuan jingshen weisheng, 2021
ObjectiveTo explore the differences of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder， and to examine the relationship between severity of clinical symptoms and cognitive function，
Zheng Chaodun, Chen Yingmei, Tan Jiuwei, Liu Guoxiong, Cai Yinglian, Lan Xiaofeng, Zhou Yanling   +6 more
doaj   +1 more source

Increased Serum Levels of Oxytocin in 'Treatment Resistant Depression in Adolescents (TRDIA)' Group. [PDF]

PLoS ONE, 2016
'Treatment-resistant depression' is depression that does not respond to an adequate regimen of evidence-based treatment. Treatment-resistant depression frequently becomes chronic.
Tsuyoshi Sasaki, Kenji Hashimoto, Yasunori Oda, Tamaki Ishima, Madoka Yakita, Tsutomu Kurata, Masaru Kunou, Jumpei Takahashi, Yu Kamata, Atsushi Kimura, Tomihisa Niitsu, Hideki Komatsu, Tadashi Hasegawa, Akihiro Shiina, Tasuku Hashimoto, Nobuhisa Kanahara, Eiji Shimizu, Masaomi Iyo   +17 more
doaj   +1 more source

Treatment-resistant major depressive disorder and assisted dying [PDF]

Journal of Medical Ethics, 2015
Competent patients suffering from treatment-resistant depressive disorder should be treated no different in the context of assisted dying to other patients suffering from chronic conditions that render their lives permanently not worth living to them.
Schuklenk, Udo, van de Vathorst, Suzanne
openaire   +3 more sources

Resistance or pseudo-resistance?

European Psychiatry, 2022
Introduction Treatment-Resistant Depression continues to represent a great challenge for clinicians. Objectives We investigated patients with history of resistance, assessing prognostic factors, response to treatments, and remission over time ...
R. Zanardi, F. Attanasio, C. De Cesare, V. Fazio, C. Colombo   +4 more
doaj   +1 more source

Ketamine as Add-On Treatment in Psychotic Treatment-Resistant Depression

Brain Sciences, 2023
Psychotic treatment-resistant depression is a complex and challenging manifestation of mood disorders in the clinical setting. Psychotic depression is a subtype of major depressive disorder characterized by mood-consistent hallucinations and/or delusions.
Maria Gałuszko-Węgielnik, Zuzanna Chmielewska, Katarzyna Jakuszkowiak-Wojten, Mariusz S. Wiglusz, Wiesław J. Cubała   +4 more
doaj   +1 more source