Results 1 to 10 of about 8,333,752 (196)

Risperidone Augmentation in Antidepressant-Resistant Somatic Symptom Disorder

open access: yesPsychiatry and Clinical Psychopharmacology
Chronic somatic symptoms are hallmarks of somatic symptom disorder (SSD), characterized by notable disruptions in the day to day lives of affected patients.
Eun Hyun Seo   +2 more
doaj   +1 more source

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

open access: yesGeneral Psychiatry, 2019
Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as ...
Aditya Somani, Sujita Kumar Kar
doaj   +1 more source

Case report: two cases of rhabdomyolysis following esketamine treatment

open access: yesFrontiers in Psychiatry
Major depressive disorder is a mental disorder affecting millions of people worldwide. A considerable proportion of patients demonstrate a lack of response to conventional treatment.
René Zeiss   +3 more
doaj   +1 more source

A new therapy modality for treatment-resistant depression: Vagal nerve stimulation

open access: yesPsychiatry and Behavioral Sciences, 2014
Objective: Although new treatment modalities are recommended for the treatment resistant depression, it has been estimated that some depressive episodes treated for an adequate duration with recommended dose of an antidepressant exhibit treatment ...
Visal Buturak, Bulent Bakar
doaj   +1 more source

Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder

open access: yesEJNMMI Research, 2020
Background Brain SPECT perfusion and PET metabolism have been, most often interchangeably, proposed to study the underlying pathological process in major depressive disorder (MDD).
Maud Tastevin   +6 more
doaj   +1 more source

Pharmacological Treatments for Patients with Treatment-Resistant Depression

open access: yesPharmaceuticals, 2020
Over a third of patients with major depressive disorder (MDD) do not have an adequate response to first-line antidepressant treatments, i.e., they have treatment-resistant depression (TRD).
Valerie L. Ruberto   +2 more
doaj   +1 more source

Appetite measures during ketamine administration in treatment-resistant mood disorders: a naturalistic study

open access: yesFrontiers in Nutrition
This study evaluated the acute and short-term effects of repeated ketamine treatment on appetite in adult inpatients with treatment-resistant mood disorders, including major depressive disorder and bipolar disorder.
Agnieszka Mechlińska   +6 more
doaj   +1 more source

Does the intensity of dissociation predict antidepressant effects 24 hours after infusion of racemic ketamine or esketamine in treatment-resistant depression? A secondary analysis from a randomized controlled trial [PDF]

open access: yesTrends in Psychiatry and Psychotherapy
Objective Ketamine and esketamine have both shown significant antidepressant effects in treatment-resistant depression (TRD) and conflicting evidence suggests that dissociation induced by these drugs could be a clinical predictor of esketamine/ketamine's
Mariana V. F. Echegaray   +18 more
doaj   +1 more source

Significant Need for a French Network of Expert Centers Enabling a Better Characterization and Management of Treatment-Resistant Depression (Fondation FondaMental)

open access: yesFrontiers in Psychiatry, 2017
BackgroundMajor depression is characterized by (i) a high lifetime prevalence of 16–17% in the general population; (ii) a high frequency of treatment resistance in around 20–30% of cases; (iii) a recurrent or chronic course; (iv) a negative impact on the
Antoine Yrondi   +28 more
doaj   +1 more source

Behavioral Activation for Treatment-resistant Depression: Theoretical Model and Intervention Protocol (BA-TRD)

open access: yesClínica y Salud. Investigación Empírica en Psicología
Background: Treatment-resistant depression (TRD) is a severe public health problem and a condition uncommonly addressed by psychological therapies.
Michel A. Reyes-Ortega   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy