Annual Review of MedicineDepressive disorders present an enormous global public health burden. A notable treatment gap exists between the prevalence of depression and our ability to provide rapid-acting, effective treatment that achieves remission. Brexanolone and zuranolone, the first US Food and Drug Administration–approved drugs for postpartum depression, signify a critical
Elizabeth, Richardson +4 more
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Neuropsychopharmacology Reports, 2020 Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki +2 more
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The effectiveness of cognitive behavioral therapy on treatment-resistant depression
Chronic Diseases Journal, 2020 BACKGROUND: Treatment-resistant depression (TRD) is a severe and chronic form of major depression. It poses significant clinical, personal, and economic burden and does not respond to antidepressants. Psychotherapy can be a suggested option.
Rezvan Sadrmohammadi, Simin Gholamrezaei
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Maintenance deep transcranial magnetic stimulation sessions are associated with reduced depressive relapses in patients with unipolar or bipolar depression [PDF]
, 2015 Introduction: Deep transcranial magnetic stimulation (dTMS) is a new form of TMS allowing safe stimulation of deep brain regions. The objective of this preliminary study was to assess the role of dTMS maintenance sessions in protecting patients with ...
ANGELETTI, Gloria +11 more
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Comparing the effects of repetitive transcranial magnetic stimulation and electroconvulsive therapy in the treatment of depression : a systematic review and meta-analysis [PDF]
, 2014 Electroconvulsive therapy (ECT) is the longest standing psychiatric treatment available and has unequivocal benefit in severe depression. However this treatment comes with a number of side effects such as memory impairment.
Micallef-Trigona, Beppe
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Cushing's syndrome masquerading as treatment resistant depression
Indian Journal of Psychological Medicine, 2016 Treatment resistant depression (TRD) is a common clinical occurrence among patients treated for major depressive disorder. A significant proportion of patients remain significantly depressed in spite of aggressive pharmacological and psychotherapeutic ...
B N Anil Kumar, Sandeep Grover
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Maintenance ECT in Recurrent Depression and Treatment Resistant Schizophrenia
Bezmiâlem Science, 2022 Objective:Electroconvulsive therapy (ECT) has been used for treatment of depression and psychosis for a long time. A less known way of use is as a maintenance treatment for keeping patients stable during remission. Recently ECT has been increasingly used
Sinem Zeynep METİN
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Treatment‐resistant major depressive disorder: Canadian expert consensus on definition and assessment [PDF]
Depression and Anxiety, 2021 Treatment-resistant depression (TRD) is a debilitating chronic mental illness that confers increased morbidity and mortality, decreases the quality of life, impairs occupational, social, and offspring development, and translates into increased costs on the healthcare system.
Yuri E. Rybak +15 more
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Informed consent decision-making in deep brain stimulation [PDF]
, 2018 Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum +6 more
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Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]
, 2002 Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B. +3 more
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