Results 71 to 80 of about 59,572 (271)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Epidemiological Signals, Knowledge Gaps, and Practice Considerations From the 2024 Functional Neurological Disorder Society International Meeting: A Conference Report With Narrative Synthesis

Medicine Bulletin, EarlyView.
ABSTRACT The 2024 International Conference on Functional Neurological Disorders brought together clinicians, researchers, advocates, and service‐user representatives to discuss recent developments in functional neurological disorder and related functional disorders.
Yadira Velazquez‐Rodriquez, Jennifer Brown, Katherine Gill   +2 more
wiley   +1 more source

No adverse events were observed in clozapine‐treated patients on extended hematologic monitoring intervals during the coronavirus pandemic in four psychiatric centers in Japan

Neuropsychopharmacology Reports, 2021
Aim As an emergency measure during the coronavirus disease pandemic, the monitoring interval for clozapine use was temporarily extended beyond the regulatory requirement in Japan, which is the safest monitoring interval worldwide. In this study, we aimed
Masahiro Hata, Michiko Fujimoto, Koji Kanai, Kenji Yoshiyama, Yoshitaka Nakatani, Daiji Nakabayashi, Saki Maemura, Shinya Kawata, Takaaki Hakozaki, Shuya Nishikura, Aiko Umemoto, Toru Sasada, Kazuhiko Iwata, Hideki Tanaka, Akiko Mamoto, Yuuki Toi, Norio Taniguchi, Makiko Saito, Yoshio Kimura, Kazuko Kishimoto, Megumi Hayami, Manabu Ikeda   +21 more
doaj   +1 more source

Effectiveness of clozapine in treatment-resistant schizophrenia

Indian Journal of Psychiatry, 2005
Clozapine has been shown to be superior to chlorpromazine in improving the positive and negative symptoms of schizophrenia. However, technical experience with clozapine in Indian patients has not been documented.To assess the improvement in psychopathology of treatment-resistant schizophrenia with clozapine therapy and to study the relationship between
Raguraman, Janakiraman, Vijay Sagar, K. John, Chandrasekaran, R.   +2 more
openaire   +3 more sources

Reduced dorso-lateral prefrontal cortex in treatment resistant schizophrenia

, 2013
Background: Treatment resistance affects up to one third of patients with schizophrenia (SCZ). A better understanding of its biological underlying processes could improve treatment.
Ota, Vanessa K. [UNIFESP], Bressan, Rodrigo A. [UNIFESP], Sintia I. Belangero, Sato, Joao, Deyvis L. Rocha, Andrea P. Jackowski, Jackowski, Andrea P. [UNIFESP], Belangero, Sintia I. [UNIFESP], Ary Gadelha, Assuncao, Idaiane [UNIFESP], Idaiane Assunção, Elisa Brietzke, Jair J. Mari, Rocha, Deyvis L. [UNIFESP], Mari, Jair J. [UNIFESP], Rodrigo A. Bressan, André Zugman, Zugman, Andre [UNIFESP], Gadelha, Ary [UNIFESP], João Sato, Brietzke, Elisa [UNIFESP], Vanessa K. Ota   +21 more
core   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Collaborative community based care for people and their families living with schizophrenia in India: protocol for a randomised controlled trial. [PDF]

, 2011
BACKGROUND: There is a large treatment gap with few community services for people with schizophrenia in low income countries largely due to the shortage of specialist mental healthcare human resources.
Thornicroft, G, Balaji, M, Leese, Morven, Varghese Mathew, Koschorke, Mirja, Sudipto Chatterjee, Mathew Varghese, McCrone, P, Rangaswamy Thara, COmmunity care for People with Schizophrenia in India (COPSI) gr, Balaji Madhumitha, Morven Leese, Hamid Dabholkar, Paul McCrone, Chatterjee, S, Dabholkar, H, John, Sujit, Koschorke Mirja, Goldsmith Kimberley, John Sujit, Chatterjee, Sudipto, Naik, S, Naik, Smita, ?, ?, Mirja Koschorke, Thara, Rangaswamy, Thornicroft Graham, null null, Varghese, M, John, S, Koschorke, M, Goldsmith, Kimberley, Vikram Patel, Dabholkar, Hamid, Sujit John, McCrone Paul, Thara, R, Balaji, Madhumitha, Kimberley Goldsmith, Leese, M, Leese Morven, Goldsmith, Kimberley; id_orcid, Thornicroft, Graham, Graham Thornicroft, Chatterjee Sudipto, Thara Rangaswamy, Goldsmith, K, Madhumitha Balaji, Patel Vikram, Varghese, Mathew, Patel, Vikram, Naik Smita, Patel, V, McCrone, Paul, Smita Naik, Dabholkar Hamid   +55 more
core   +1 more source

Law enforcement policies for individuals with intellectual and developmental disabilities: A mixed‐methods analysis

Criminology &Public Policy, EarlyView.
Abstract Research Summary Individuals with intellectual and developmental disabilities (IDDs) face an elevated risk of victimization relative to their peers. Victims with IDD may view police departmental websites or policies to identify available accommodations in deciding to report their experience. The current study employs a convergent mixed‐methods
Cooper A. Maher, Brittany E. Hayes, Martha McCullough, Jacquelyn Burckley, Ráchael A. Powers, Amanda K. Simmons, Leigh Anne McKingsley   +6 more
wiley   +1 more source

Efficacy and tolerability of clozapine versus quetiapine in treatment-resistant schizophrenia

Indian Journal of Psychological Medicine, 2017
Objectives: To compare the efficacy and tolerability of clozapine and quetiapine in patients with treatment-resistant schizophrenia (TRS). Patients and Methods: In this prospective, randomized, open label study of 14 weeks, 53 patients with schizophrenia
Mitesh Kumar, B S Chavan, Ajeet Sidana, Subhash Das   +3 more
doaj   +1 more source

Antipsychotic medication for people with first episode schizophrenia: an exploratory economic analysis of alternative treatment algorithms [PDF]

Available clinical evidence suggests that the newer antipsychotics are similar to conventional antipsychotics for positive symptom control. It has been suggested that they may also be superior for negative symptoms and side effects, but the evidence for ...
Linda Davies, Shon Lewis
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