Results 111 to 120 of about 21,878,726 (386)

Estimating heterogeneous treatment effects in nonstationary time series with state-space models [PDF]

arXiv, 2018
Randomized trials and observational studies, more often than not, run over a certain period of time. The treatment effect evolves during this period which provides crucial insights into the treatment response and the long-term effects. Many conventional methods for estimating treatment effects are limited to the i.i.d.
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Reporting results of cancer treatment

Cancer, 1981
On the initiative of the World Health Organization, two meetings on the Standardization of Reporting Results of Cancer Treatment have been held with representatives and members of several organizations.
A. Miller, B. Hoogstraten, M. Staquet, A. Winkler   +3 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Retrospective analysis of clinical data from 171 low-income patients with hemophilia in Shandong Province

Scientific Reports
To enhance attention on low-income patients with hemophilia, it is essential to urge governments and coagulation factor manufacturers to increase their investment in hemophilia care.
Jie Wang, Yan Cheng, Yunhai Fang, Cuicui Qiao, Tiantian Wang, Hehe Wang, Xueqin Zhang, Qiang Li   +7 more
doaj   +1 more source

Navigated transcranial magnetic stimulation in rehabilitation of traumatic frontal lobes injury

Анналы клинической и экспериментальной неврологии, 2017
Traumatic injury of frontal lobes has severe impact on socialadaptation due to alterations in cognitive function and behavior.Considering the low efficacy of conventional rehabilitationmethods, the development of complementary approaches isneeded ...
O. R. Dobrushina, I. V. Sidyakina, K. V. Lyadov, T. V. Shapovalenko, V. E. Sinitsin, E. A. Mershina, E. V. Pechenkova, S. A. Kazymaev, A. D. Румшиская   +8 more
doaj   +1 more source

GraphITE: Estimating Individual Effects of Graph-structured Treatments [PDF]

arXiv, 2020
Outcome estimation of treatments for target individuals is an important foundation for decision making based on causal relations. Most existing outcome estimation methods deal with binary or multiple-choice treatments; however, in some applications, the number of treatments can be significantly large, while the treatments themselves have rich ...
arxiv  

Double/Debiased Machine Learning for Treatment and Structural Parameters

, 2017
We revisit the classic semiparametric problem of inference on a low dimensional parameter θ_0 in the presence of high-dimensional nuisance parameters η_0.
V. Chernozhukov, D. Chetverikov, Mert Demirer, E. Duflo, Christian Hansen, Whitney Newey, J. Robins   +6 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

European Respiratory Journal, 2004
The Standards for the Diagnosis and Treatment of Patients with COPD document 2004 updates the position papers on chronic obstructive pulmonary disease (COPD) published by the American Thoracic Society (ATS) and the European Respiratory Society (ERS) in ...
B. Celli, W. Macnee, A. Agustí, A. Anzueto, B. Berg, A. Buist, P. Calverley, N. Chavannes, T. Dillard, Bonnie F. Fahy, A. Fein, J. Heffner, S. Lareau, P. Meek, F. Martinez, W. McNicholas, J. Muris, E. Austegard, R. Pauwels, S. Rennard, A. Rossi, N. Siafakas, B. Tiep, J. Vestbo, E. Wouters, R. Zuwallack   +25 more
semanticscholar   +1 more source