Results 231 to 240 of about 33,585,029 (332)

Tumour-associated macrophages as treatment targets in oncology

Nature Reviews Clinical Oncology, 2017
A. Mantovani, F. Marchesi, A. Malesci, L. Laghi, P. Allavena   +4 more
semanticscholar   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Xuebijing alleviates high-voltage electrical burn-induced acute kidney injury by inhibiting neutrophils and inflammation. [PDF]

Sci Rep
He X, Li N, Ma L, Yang M, Ren L, Hao J, Xue X, Pang Y.   +7 more
europepmc   +1 more source

The Treatment of Syphilis [PDF]

BMJ, 1872
openaire   +5 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance. [PDF]

Schizophrenia (Heidelb)
Tepper A, Vásquez J, Díaz Dellarossa C, Ramirez-Mahaluf JP, Aguirre J, Barbagelata D, Aceituno D, Undurraga J, Nachar R, Mena C, McCutcheon RA, McGuire P, Gonzalez-Valderrama A, Crossley NA.   +13 more
europepmc   +1 more source

Double/Debiased Machine Learning for Treatment and Structural Parameters

, 2017
V. Chernozhukov, D. Chetverikov, Mert Demirer, E. Duflo, Christian Hansen, Whitney K. Newey, J. Robins   +6 more
semanticscholar   +1 more source

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

New England Journal of Medicine, 1993
Diabetes Control, D. Nathan, S. Genuth, J. Lachin, P. Cleary, O. Crofford, M. Davis, L. Rand, C. Siebert   +8 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Associations Between Laser Treatment Utilization, Regional Access, and Vision-Threatening Diabetic Retinopathy in Northwest Tanzania: A Retrospective Study. [PDF]

Cureus
Woodward R, Mwanansao C, Peck RN, Sun G.
europepmc   +1 more source