Results 241 to 250 of about 13,587,543 (295)

The treatment of alcohol abuse and alcoholism: psychosocial and pharmacological management.

, 2004
BERNARDI, MAURO, CAPUTO F., Addolorato G., Alcoholism Treatment Study Group, BERNARDI M., CAPUTO, FABIO, ALCOHOLISM TREATMENT STUDY GROUP., Gasbarrini G.   +7 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Healthcare Utilization and Recovery Duration After Ankle Fracture: A Claims-Based Study of Timeline, Costs and Complications. [PDF]

J Eval Clin Pract
Weinstein Dpm RB, Beckley SJ, Karim M, Stinton SK, Branch TP.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Melatonin-selenium nanoformulation: a promising therapeutic strategy against Ehrlich ascites carcinoma. [PDF]

Sci Rep
Morad HM, Abdel-Aziz AF, Madkour MM.
europepmc   +1 more source

Comparable effectiveness of intensive intravenous and less intensive immunosuppressive treatment in retroperitoneal fibrosis: a retrospective real-world cohort study. [PDF]

Rheumatol Int
Niksińska A, Kruszewski R, Wąsik M, Kania-Pudło M, Kisiel B, Malczuk E, Koblowski J, Tłustochowicz W.   +7 more
europepmc   +1 more source