Results 61 to 70 of about 33,585,029 (332)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Treatment of hypothyroidism

Journal of Education, Health and Sport, 2018
Małecka Paulina, Małecka-Kacpura Justyna, Fabian-Danielewska Anna. Treatment of hypothyroidism. Journal of Education, Health and Sport. 2018;8(12):87-94. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1931455 http://ojs.ukw.edu.pl/index.php/johs/article/view/6346 https://pbn.nauka.gov.pl/sedno-webapp/works/889853 The journal ...
Paulina Małecka, Anna Fabian-Danielewska, Justyna Małecka-Kacpura   +2 more
openaire   +4 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Heat treatment for superalloy [PDF]

, 1987
A cobalt-free nickel-base superalloy composed of in weight % 15 Cr-5 Mo-3.5 Ti-4 Al-0.07 (max) C-remainder Ni is given a modified heat treatment.
Harf, Fredric H.
core   +1 more source

Diagnosis and treatment of canine hypoadrenocorticism [PDF]

, 2018
Canine hypoadrenocorticism (Addison’s disease), the ‘great pretender’ of internal medicine, is a disease that should be frequently considered as a differential diagnosis of several clinical presentations, albeit it is less commonly the actual cause of ...
Gunn, Eilidh, Ramsey, Ian, Spence, Susanna   +2 more
core   +1 more source

Exploring treatment options in cancer: tumor treatment strategies

Signal Transduction and Targeted Therapy
Traditional therapeutic approaches such as chemotherapy and radiation therapy have burdened cancer patients with onerous physical and psychological challenges.
Beilei Liu, Hongyu Zhou, Licheng Tan, Kin To Hugo Siu, Xin-Yuan Guan   +4 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.

European Heart Journal, 2021
T. McDonagh, M. Metra, M. Adamo, R. S. Gardner, A. Baumbach, Michael Böhm, H. Burri, J. Butler, J. Čelutkienė, O. Chioncel, John G. Cleland, A. Coats, M. Crespo-Leiro, Dimitrios Farmakis, Martine Gilard, Stephane Heymans, Arno W. Hoes, Tiny Jaarsma, E. A. Jankowska, M. Lainščak, C. S. Lam, A. Lyon, J. J. McMurray, A. Mebazaa, Richard Mindham, Claudio Muneretto, Massimo Francesco Piepoli, Susanna Price, G. Rosano, F. Ruschitzka, Anne Kathrine Skibelund   +30 more
semanticscholar   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Treatment of irritable bowel syndrome [PDF]

, 2005
Irritable bowel syndrome is characterised by diverse symptoms including abdominal pain, altered bowel function (increased bowel frequency, constipation), bloating, abdominal distension, the sensation of incomplete evacuation, and the increased passage of
Farthing, Michael
core   +1 more source