Results 31 to 40 of about 8,174,546 (314)

Compliance to patching in the treatment of amblyopia

open access: yesSaudi Journal of Ophthalmology, 2012
To evaluate compliance of amblyopic patients to patching, and to identify reasons of poor compliance and suggest methods to overcome the problem.We conducted a cross-sectional, retrospective study that included 37 families with a child diagnosed with unilateral amblyopia (age range 3-16 years) and attending the Pediatrics Ophthalmology clinic at the ...
Al-Yahya, Ahmed   +5 more
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Development and reliability and validity test of the treatment compliance scale for patients with chronic hepatitis B

open access: yesHuli yanjiu, 2021
ObjectiveTo develop a scale for evaluating treatment compliance of patients with chronic hepatitis B (CHB) and test its reliability and validity.MethodsCombining literature review,expert consultation and group discussion an item pool was formed.According
ZUO Feifei   +4 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Unmasking the Determinants of Loss to Follow-Up in Pulmonary Tuberculosis: A Study in Selangor, Malaysia

open access: yesTropical Medicine and Infectious Disease
Adherence to the 6-month tuberculosis (TB) treatment regimen is challenging due to its duration and side effects, with various factors influencing patient compliance. A retrospective cross-sectional study was conducted among newly diagnosed pulmonary TB (
Sumarni Mohd Ghazali   +14 more
doaj   +1 more source

Evaluation of the probation results of 2010 in Samsun Mental Health Hospital and the compliance with treatment in individuals referred from the centers outside of the city center of Samsun [PDF]

open access: yesDüşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2013
Aim: In this study, we aimed at evaluating the probations results and compliance with treatment in patients referred to the Samsun Mental Health Hospital from the centers outside of the city of Samsun.
abdullah akpinar   +2 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Effects of phased focused nursing on liver function and self-care ability in chronic hepatitis B patients

open access: yesFrontiers in Medicine
AimChronic hepatitis B (CHB) patients often face challenges related to liver function recovery, psychological wellbeing, and self-care ability during treatment.
Dongcang Hou   +10 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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