Results 51 to 60 of about 798,589 (313)

Enforcement and over-compliance [PDF]

Economists generally view environmental enforcement as a tool to secure compliance with regulations. This paper demonstrates that credible enforcement significantly increases statutory over-compliance with regulations as well.
Ward, Michael B., Shimshack, Jay P.
core   +4 more sources

Effects of phased focused nursing on liver function and self-care ability in chronic hepatitis B patients

Frontiers in Medicine
AimChronic hepatitis B (CHB) patients often face challenges related to liver function recovery, psychological wellbeing, and self-care ability during treatment.
Dongcang Hou, Fei Liu, Dongjie Hou, Chunrong Ping, Wenying He, Zeyang Chen, Ganlu Tian, Tian Qin, Wenjing Zhou, Menghui Xu, Xiaoman Ruan   +10 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Effects of Drug Compliance on Quality of Life in Patients with Epilepsy

Archives of Epilepsy, 2016
Objectives:The aim of the present descriptive study was to determine the effect of patient compliance with antiepileptic drug therapy on quality of life.Methods:The study population comprised 115 patients with epilepsy who applied to the neurology clinic
Gülden ACAROĞLU, Emel YILMAZ
doaj   +1 more source

FIXED ETIOPATHOGENETIC COMBINATION OF DRUGS TO TREAT ARTERIAL HYPERTENSION

Медицинский совет, 2017
Fixed combinations of antihypertensive drugs are more actively used in practice for therapy of arterial hypertension and on the whole are positively assessed by doctors and by patients.
M. P. Savenkov, S. N. Ivanov, M. P. Mikhailusova, М. V. Borschevskaya, I. N. Okuneva, L. A. Solomonova, А. M. Savenkova   +6 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Evaluation of real-world follow-up methods and their association with adherence and safety in adjuvant breast cancer therapy: a retrospective study

Frontiers in Oncology
AimTo compare the associations between different follow-up management methods—telephone, WeChat, and mini-program—and treatment compliance, safety, quality of life, and self-management in breast cancer patients receiving adjuvant therapy.MethodsThis ...
Na Li, Na Li, Qian Zhang, Qian Zhang, Xiaomei Yang, Xiaomei Yang, Xiaoli Li, Xiaoli Li, Xixi Tian, Wei Li, Wei Li, Lili Ren, Lili Ren, Hua Yang, Hua Yang   +14 more
doaj   +1 more source

Evaluation of the probation results of 2010 in Samsun Mental Health Hospital and the compliance with treatment in individuals referred from the centers outside of the city center of Samsun [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2013
Aim: In this study, we aimed at evaluating the probations results and compliance with treatment in patients referred to the Samsun Mental Health Hospital from the centers outside of the city of Samsun.
abdullah akpinar, osman şalis, umut mert aksoy   +2 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The role of treatment compliance in combination therapy for heart failure and possibilities of its correction: Generalization of Russian and world experience

Терапевтический архив, 2014
Chronic heart failure (CHF) is a serious health problem today. Despite all advances in modern medicine, the high morbidity and mortality rates of CHF force physicians to search for new more effective methods for its control.
E S Trofimov, A S Poskrebysheva
doaj