Results 111 to 120 of about 23,655,214 (287)

Analyzing Treatment Effect by Integrating Existing Propensity Score and Outcome Regressions with Heterogeneous Covariate Sets

Mathematics
Analyzing treatment or exposure effect is a major research theme in scientific studies. In the current big-data era where multiple sources of data are available, it is of interest to perform a synthesized analysis of treatment effects by integrating ...
Yi-Hau Chen, Szu-Yuan Hsu, Jie-Huei Wang, Chien-Chou Su   +3 more
doaj   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Brain‐derived tau to measure treatment effect in Alzheimer's disease and frontotemporal dementia

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Brain‐derived tau (BD‐tau) measures tau specifically from brain‐derived sources and can differentiate Alzheimer's disease (AD) from other diseases. This study investigated BD‐tau as a potential biomarker of treatment effect.
Cassandra Marotta, Fernando Gonzalez‐Ortiz, Michael Turton, Henrik Zetterberg, Peter Harrison, Christopher M. Hovens, Benjamin Sinclair, Terence J. O'Brien, Kaj Blennow, Lucy Vivash   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Mental Health Parity Legislation, Cost-Sharing and Substance Abuse Treatment Admissions [PDF]

Treatment is highly cost-effective in reducing an individual’s substance abuse (SA) and associated harms. However, data from Treatment Episodes (TEDS) indicate that per capita treatment admissions substantially lagged behind increases in heavy drug use ...
Swati Mukerjee, Dhaval M. Dave
core  

O Impacto do Programa Saúde da Família Sobre a Saúde das Crianças da Área Rural do Brasil

Revista de Economia e Sociologia Rural
Resumo: Este trabalho buscou analisar o impacto do Programa Saúde da Família (PSF) sobre a saúde das crianças (menores de 12 anos) da área rural do Brasil com base nos dados da PNAD (2008), utilizando os métodos Propensity Score Matching e Mínimos ...
Anderson Moreira Aristides dos Santos, Paulo de Andrade Jacinto   +1 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Preventing the Entry of Weapons of Mass Effect Into the United States [PDF]

, 2006
A report discussing the vulnerabilities of the United States in regards to a terrorist delivery of a weapon of mass effect (WME).
Homeland Security Advisory Council Weapons of Mass Effect Task Force
core  

Effect of Age Factor on Corneal Cross-linking Treatment of Keratoconus Patients

, 2012
Pur po se: To evaluate the effect of age on corneal cross-linking treatment in keratoconus patients. Ma te ri al and Met hod: We retrospectively evaluated forty-nine eyes of 45 patients with keratoconus that were applied corneal cross-linking treatment.
Erdem Yüksel, Murat Aslankurt, ASLAN, LOKMAN, ÖZDEMİR, MURAT, Lokman Aslan, Ahmet Metin Başkan, BAŞKAN, AHMET METİN, YÜKSEL, ERDEM, ASLANKURT, MURAT, Murat Özdemir   +9 more
core   +1 more source