Results 151 to 160 of about 31,464 (260)

Long‐term efficacy and safety of romiplostim plus immunosuppressive therapy as first‐line treatment in patients with aplastic anaemia: 2‐year interim analysis of observational study of two clinical trials

open access: yes
British Journal of Haematology, EarlyView.
Jong Wook Lee   +19 more
wiley   +1 more source

Clinical and Economic Burden of Obesity and Cardiovascular Disease Among Medicare Fee‐For‐Service Beneficiaries

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This retrospective cohort study described clinical outcomes, healthcare resource utilisation (HCRU), and costs among Medicare beneficiaries with or without obesity and stratified by cardiovascular disease (CVD) risk. Materials and Methods Using Medicare FFS claims (Jan 2016–Dec 2022), beneficiaries were indexed after 12 months of ...
Jiayin Xue   +9 more
wiley   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Online interest in calcitonin gene‐related peptide‐therapies: An infodemiology study using Google trends

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate changes in public interest in calcitonin gene‐related peptide therapies associated with major product lifecycle milestones using online search data from the United States and Europe. Background Calcitonin gene‐related peptide therapies have transformed migraine treatment, but the impact of key product lifecycle milestones
Bradley Ong   +5 more
wiley   +1 more source

UltRaSoUnd‐guided evaLuAtion of metabolic health in a cohort of midlife women with HIV: The URSULA study

open access: yesHIV Medicine, EarlyView.
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno   +13 more
wiley   +1 more source

DNA Nanostructures for siRNA Delivery. [PDF]

open access: yesBioconjug Chem
Madhanagopal BR   +2 more
europepmc   +1 more source

Frailty and associated clinical factors among Japanese people with HIV: A multicentre cross‐sectional study using the revised Japanese Cardiovascular Health Study criteria

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Frailty is relevant to HIV care across middle and later life, yet Japanese data remain limited. We evaluated frailty, prefrailty and associated factors in Japanese people with HIV using the revised Japanese Cardiovascular Health Study (J‐CHS) criteria.
Hideta Nakamura   +15 more
wiley   +1 more source

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