Results 171 to 180 of about 7,811,485 (314)

Evaluation of the relationship between the psychosocial impact of dental appearance and self-perceived esthetic treatment need among dental students. [PDF]

BMC Med Educ
Akbeyaz Şivet E, Sezer B, Karanlık U, Kargül B.   +3 more
europepmc   +1 more source

Artemether-Lumefantrine Treatment Failure despite adequate lumefantrine day 7 Concentration in a Traveller with Plasmodium Falciparum Malaria after Returning from Tanzania. [PDF]

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa.
Färnert, Anna, Karlsson, Lillemor, Lindegårdh, Niklas, Rono, Josea, Sparrelid, Elda, Tolfvenstam, Thomas, Ursing, Johan   +6 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Comparative Assessment of Smile Attractiveness Perception and Treatment Need Across Dental Professionals and Laypersons. [PDF]

Cureus
Ravichandra S, Riyaz K, Manjappa LS, Talwar A, Narsimha Mogaveera NK, Ghosh PP, Gupta S.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Disparity in immigrant compulsory care assignment: discrimination or response to treatment need. [PDF]

Gen Psychiatr
Segal SP, Badran L, Rimes L, Lakra V.
europepmc   +1 more source

Assessment of orthodontic borderline treatment need: A comparison of two aesthetic indices. [PDF]

Prog Orthod, 2022
Sampson A, Passan N, Jeremiah HG, Kirschen R.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diagnostic accuracy of the Oral Aesthetic Subjective Impact Score (OASIS) questionnaire for orthodontic treatment need in Nepal: a hospital-based study. [PDF]

BMC Oral Health
Pandey S, Gyawali R, Pokharel PR, Chaudhary A, Sangroula S, Bhattarai S.   +5 more
europepmc   +1 more source

Malocclusion complexity and orthodontic treatment need in children with autism spectrum disorder. [PDF]

Clin Oral Investig, 2022
Meuffels SA, Kuijpers-Jagtman AM, Tjoa STH, Bonifacio CC, Carvajal Monroy PL.   +4 more
europepmc   +1 more source