Results 191 to 200 of about 7,811,485 (314)

Link Between Perception of Treatment Need and Craving Reports in Addiction. [PDF]

Front Psychiatry, 2021
Lambert L, Serre F, Thirioux B, Jaafari N, Roux P, Jauffret-Roustide M, Lalanne L, Daulouède JP, Auriacombe M.   +8 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Unmet treatment need: The size of the gap for alcohol and other drugs in Australia. [PDF]

Drug Alcohol Rev
Ritter A, O'Reilly K.
europepmc   +1 more source

Oral health-related quality of life and orthodontic treatment need in thalassemia major patients. [PDF]

Dent Res J (Isfahan), 2022
Tabesh A, Abbasi F, Shavakhi M, Mahmood M.   +3 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Sense of coherence and its relation to self perceived dental appearance and normative orthodontic treatment need among 12-year-old children. [PDF]

J Oral Biol Craniofac Res
Susmitha TS, Sukhabhogi JR, Doshi D.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Assessment of Orthodontic Treatment Need among School-Aged Children Using the Index of Orthodontic Treatment Need: A Cross-Sectional Study.

J Pharm Bioallied Sci
Kapoor P, Singh H.
europepmc   +1 more source

The Intersection of Rurality, Unmet Treatment Need, and Cannabis Use for Adults with Chronic Pain. [PDF]

Cannabis
Appleseth H, Azizoddin DR, Cohn AM.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source