Results 211 to 220 of about 3,364,478 (267)

An epidemiological study on early orthodontic treatment need among eastern Saudi Arabian children in the mixed dentition stage. [PDF]

Sci Rep
Madiraju GS, Almugla YM, Mohan R, Alnasser BM.   +3 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

HIV status and substance use disorder treatment need and utilization among adults in the United States, 2015-2019: Implications for healthcare service provision and integration. [PDF]

J Subst Use Addict Treat
West BS, Krasnova A, Philbin MM, Diaz JE, Kane JC, Mauro PM.   +5 more
europepmc   +1 more source

Posttraumatic stress disorder in people who use drugs: syringe services program utilization, treatment need, and preferences for onsite mental health care. [PDF]

Harm Reduct J
López-Castro T, Sohler N, Riback L, Bravo G, Ohlendorf E, Ghiroli M, Fox AD.   +6 more
europepmc   +1 more source

La necesidad de tratamiento ortodóncico desde un perfil bibliométrico

Revista Cubana de Estomatología
Isabel Martínez Brito, Luis Soto Cantero, Martha Lidia Rivero LLops, Gudelia Alemán Estévez, Alfredo García Martínez, Ramón Yunior Almeida Bravo   +5 more
doaj  

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Number‐Needed‐to‐Treat (NNT) – Needs Treatment with Care

Basic & Clinical Pharmacology & Toxicology, 2006
Abstract: The “number‐needed‐to‐treat” (NNT) was introduced about 15 years ago and has gained widespread use. It has been claimed to be “easy to understand” and gives “intuitive meaning”. When used to measure the effectiveness of interventions targeting chronic disease processes e.g.
Christensen, Palle Mark, Kristiansen, Ivar Sønbø   +1 more
openaire   +2 more sources

THE URGENT NEED FOR TREATMENT EVALUATION

Psychiatric Services, 1967
supposed to do? Does it do the job better than similar ones? After the initial cost, does it do it more chea )ly? %Vhat is the evidence for such claims? We must ask the same questions about products and programs intended for psychiatric patients. Perhaps we need a kind of Consumer Reports to help us evaluate better the efficacy of psychotherapeutic ...
G K, Lumry, W, Simon
openaire   +2 more sources

Perspectives on Treatment Needs in Schizophrenia

British Journal of Psychiatry, 1996
Schizophrenia is one of the most severe and debilitating major psychiatric diseases, with a yearly prevalence of 0.4–0.8% in the general population (Dohrenwend, 1980; Flekkoy, 1987) and a lifetime risk of 1–1.5% (Regier et al, 1984; Robins et al, 1984). It is the prototype of a severe mental illness, with the capacity to disrupt routine daily functions
U, Meise, W W, Fleischhacker
openaire   +2 more sources

Unmet needs in the treatment of glioblastoma

Expert Review of Anticancer Therapy, 2009
Glioblastoma multiforme (GBM) is among the most difficult of tumors to treat and, despite all efforts, median overall survival (mOS) remains at approximately 12 months [1].
Melike, Mut, David, Schiff
openaire   +2 more sources

The Prevalence of Orthodontic Treatment Need

British Journal of Orthodontics, 1992
The prevalence of unmet orthodontic treatment need amongst 955 12-year-old Sheffield children has been assessed using the Index of Orthodontic Treatment Need [I.O.T.N.]. The Index was found to be quick and simple to use, and demonstrated very good levels of intra-examiner agreement.
openaire   +2 more sources