Results 241 to 250 of about 16,286,678 (305)

The impact of unmet treatment need on oral health related quality of life: a questionnaire survey. [PDF]

BMC Oral Health
Shetty A, Bhandary R, Ahuja D, Venugopalan G, Grossi E, Tartaglia GM, Khijmatgar S.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

New South Wales alcohol and other drug service providers' perceptions of the relative importance of client variables for determining treatment need. [PDF]

Drug Alcohol Rev
Larance B, Ingram I, Haynes C, Buckfield L, Goh CWM, Kelly PJ.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

A cross-sectional study to correlate oral hygiene habit among orthodontic patients with their clinical findings and periodontal treatment need. [PDF]

BMC Oral Health
Mansoor M, Monis D, Anjum R, Siddiqui TA, Mir HA, Nazir R.   +5 more
europepmc   +1 more source

Dental caries status and treatment need among pregnant women attending antenatal clinics in Dar-Es-Salaam region, Tanzania. [PDF]

BMC Oral Health
Msagati FR, Mandari GJ, Simon ENM.
europepmc   +1 more source

Adherence to Exercise in People with Lung or Head and Neck Cancer: Self-Reported Symptoms and Motivation During Cancer Treatment Need to Be Considered. [PDF]

J Clin Med
Pedroso M, Grigoletto I, Oliveira L, Martins S, Costa L, Pozo K, Borges P, Regio L, Duarte I, Cavalheri V, Ramos E.   +10 more
europepmc   +1 more source

Psychometric properties of the Arabic version of the perceived prosthodontic treatment need scale: Exploratory and confirmatory factor analyses. [PDF]

PLoS One
Sharka R.
europepmc   +1 more source

An epidemiological study on early orthodontic treatment need among eastern Saudi Arabian children in the mixed dentition stage. [PDF]

Sci Rep
Madiraju GS, Almugla YM, Mohan R, Alnasser BM.   +3 more
europepmc   +1 more source