Results 251 to 260 of about 7,811,485 (314)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Heterogeneity in Unmet Treatment Need and Barriers to Accessing Mental Health Services Among U.S. Military Service Members with Serious Psychological Distress. [PDF]

Adm Policy Ment Health
Dunbar MS, Breslau J, Collins R, Beckman R, Engel CC.   +4 more
europepmc   +1 more source

Disease burden, clinical management and unmet treatment need of patients with moderate to severe atopic dermatitis; consensus statements, insights and practices from CERTADE (Central/Eastern EU, Russia, Turkiye AD Experts) Delphi panel. [PDF]

Front Med (Lausanne)
Trzeciak M, Rudnicka L, Arenberger P, Engin B, L'vov A, Alper S, Alpsoy E, Benáková N, Bobko S, Borlu M, Czarnecka-Operacz M, Elisyutina O, Ergun T, Ertam I, Fedenko E, Filipovská O, Fomina D, Gadzhigoroeva A, Kojanová M, Lesiak A, Michenko A, Murashkin N, Owczarek W, Özkaya E, Plzáková Z, Reich A, Selerova M, Gurbuz BA.   +27 more
europepmc   +1 more source

La necesidad de tratamiento ortodóncico desde un perfil bibliométrico

Revista Cubana de Estomatología
Isabel Martínez Brito, Luis Soto Cantero, Martha Lidia Rivero LLops, Gudelia Alemán Estévez, Alfredo García Martínez, Ramón Yunior Almeida Bravo   +5 more
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Empiric NSU treatment needs updating

Sexually Transmitted Infections, 2014
The recent paper by Khosropour et al 1 highlighted current management issues related to non-specific urethritis (NSU) treatment and adherence. It follows accumulating recent literature surrounding the management of NSU, especially with regard to Mycoplasma genitalium urethritis, where studies highlight significant treatment failure using standard ...
Sally, Murray, Lewis, Marshall
openaire   +2 more sources

Women's Health Needs Special Treatment

Health & Social Work, 2001
This issue features articles on subjects critically important to women's health and well-being. To these familiar topics, the authors bring fresh assessments of the multifaceted components of health for women today, a collection as timely as tomorrow's news, and as basic to social work practice as health itself.
S, Keigher, S, Taylor-Brown
openaire   +2 more sources

Women’s hearts need special treatment

International Journal of Behavioral Medicine, 2002
Coronary heart disease (CHD) is the leading cause of death for both men and women in the Western world. Some studies show that the observed decline in cardiovascular mortality is not as pronounced among women as among men. There is a growing awareness that most earlier studies both on primary and secondary risk factors, diagnosis, prognosis, and ...
Gunilla, Burell, Brittmarie, Granlund
openaire   +2 more sources

Congenital melanocytic nevi needing treatment

Dermatologic Therapy, 2005
Patients presenting with congenital melanocytic nevi (CMN) need individualized treatment based upon nevus size, thickness, location, risk for developing melanoma, and psychological characteristics of the patient and family. The present authors review CMN types and prognoses, as well as absolute and relative indications for treatment. Risks and benefits
Jennifer, Tromberg, Bruce, Bauer, Cristiane, Benvenuto-Andrade, Ashfaq A, Marghoob   +3 more
openaire   +2 more sources