Results 31 to 40 of about 382,036 (268)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Chemical Characterization of Stabilized and Carbonized Polyacrylonitrile (PAN) Fibers Treated with Oleic Acid.

MATEC Web of Conferences, 2014
Polyacrylonitrile (PAN) fiber is the best precursor for carbon fibers due to high carbon content after heat treatment. After the polymer was spun into fibers, the fibers will undergo pretreatment process with chemical solution known as post spinning ...
Salleh Shahrul Nizam Md, Abdullah Mohamad Zaki, Wahab Azmi Abdul   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Effect of the Sizing Removal Methods of Fiber Surface on the Mechanical Performance of Basalt Fiber-Reinforced Concrete

Fibers
In this study, comprehensive analyses were used to evaluate the physical and chemical properties of basalt fibers, employing a variety of instruments. Additionally, heat treatment and solvent treatment methods were used to eliminate the sizing present on
Yeou-Fong Li, Jia-Yin Hung, Jin-Yuan Syu, Shih-Han Chen, Chih-Hong Huang, Shu-Mei Chang, Wen-Shyong Kuo   +6 more
doaj   +1 more source

Study on two eco-friendly surface treatments on Luffa cylindrica for development of reinforcement and processing materials

Journal of Materials Research and Technology, 2021
The development of new materials or the improvement of their mechanical properties is a constant challenge in science. Numerous researchers have increasingly concentrated efforts to obtain new and more environmentally friendly materials using natural ...
Maria-Belen Martinez-Pavetti, Lucas Medina, Magdalena Espínola, Magna Monteiro   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Comparative Evaluation of Chemical Treatment on the Physical and Mechanical Properties of Areca Frond, Banana, and Flax Fibers

Journal of Natural Fibers, 2022
The present work aims to understand the effect of chemical treatment on the physical and mechanical characteristics of the natural fibers, namely, areca frond fibers, banana, and flax fibers. Chemical reagents viz.
Srinivas Shenoy Heckadka, Suhas Yeshwant Nayak, Thomas Joe, Jacob Zachariah N, Sonia Gupta, Anil Kumar N V, Marta Matuszewska   +6 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source