Results 51 to 60 of about 5,044,916 (330)

UK Alcohol Treatment trial: client-treatment matching effects [PDF]

open access: yes, 2008
Aim To test a priori hypotheses concerning client–treatment matching in the treatment of alcohol problems and to evaluate the more general hypothesis that client–treatment matching adds to the overall effectiveness of treatment. Design Pragmatic,
Beutler   +67 more
core   +1 more source

Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT KAT6A syndrome (Arboleda–Tham syndrome) is a rare disorder caused by heterozygous pathogenic variants in KAT6A, a histone acetyltransferase essential for chromatin remodeling and hematopoietic stem cell function. While neurodevelopmental features are well established, hematologic manifestations are underrecognized.
Ye Jee Shim   +8 more
wiley   +1 more source

Time to develop aspiration pneumonia and its predictors among stroke patients admitted at specialized hospitals in Western Amhara during the armed conflict period, 2024

open access: yesScientific Reports
Stroke, characterized by a sudden neurologic deficit due to reduced cerebral perfusion, often leads to complications such as aspiration pneumonia. This acute lung infection occurs when substances from the gastrointestinal tract, including endogenous ...
Addisu Getie   +5 more
doaj   +1 more source

To Adjust or Not to Adjust? Sensitivity Analysis of M-Bias and Butterfly-Bias [PDF]

open access: yes, 2014
"M-Bias," as it is called in the epidemiologic literature, is the bias introduced by conditioning on a pretreatment covariate due to a particular "M-Structure" between two latent factors, an observed treatment, an outcome, and a "collider." This ...
Ding, Peng, Miratrix, Luke
core   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Treatment outcomes and associated factors of stroke in Ethiopia: a systematic review and meta-analysis

open access: yesBMC Cardiovascular Disorders
Introduction Stroke is characterized by a sudden onset of focal or global neurological deficits resulting from reduced cerebral blood flow. Poor treatment outcomes are primarily caused by uncontrolled blood pressure and delayed hospital arrival.
Addisu Getie   +2 more
doaj   +1 more source

Outcome-based pricing for new pharmaceuticals via rebates [PDF]

open access: yes, 2020
The price of new brand-name prescription drugs has been rising fast in the United States. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year.
Adida, E
core  

Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme [PDF]

open access: yes, 2016
Aims We investigated the association between worsening renal function (WRF) that occurs during renin–angiotensin–aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared ...
Brenner   +21 more
core   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein   +3 more
wiley   +1 more source

A Statistical Model for Stroke Outcome Prediction and Treatment Planning

open access: yes, 2016
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit   +3 more
core   +1 more source

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