Results 51 to 60 of about 5,044,916 (330)
UK Alcohol Treatment trial: client-treatment matching effects [PDF]
Aim To test a priori hypotheses concerning client–treatment matching in the treatment of alcohol problems and to evaluate the more general hypothesis that client–treatment matching adds to the overall effectiveness of treatment. Design Pragmatic,
Beutler +67 more
core +1 more source
Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome
ABSTRACT KAT6A syndrome (Arboleda–Tham syndrome) is a rare disorder caused by heterozygous pathogenic variants in KAT6A, a histone acetyltransferase essential for chromatin remodeling and hematopoietic stem cell function. While neurodevelopmental features are well established, hematologic manifestations are underrecognized.
Ye Jee Shim +8 more
wiley +1 more source
Stroke, characterized by a sudden neurologic deficit due to reduced cerebral perfusion, often leads to complications such as aspiration pneumonia. This acute lung infection occurs when substances from the gastrointestinal tract, including endogenous ...
Addisu Getie +5 more
doaj +1 more source
To Adjust or Not to Adjust? Sensitivity Analysis of M-Bias and Butterfly-Bias [PDF]
"M-Bias," as it is called in the epidemiologic literature, is the bias introduced by conditioning on a pretreatment covariate due to a particular "M-Structure" between two latent factors, an observed treatment, an outcome, and a "collider." This ...
Ding, Peng, Miratrix, Luke
core +1 more source
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small +3 more
wiley +1 more source
Introduction Stroke is characterized by a sudden onset of focal or global neurological deficits resulting from reduced cerebral blood flow. Poor treatment outcomes are primarily caused by uncontrolled blood pressure and delayed hospital arrival.
Addisu Getie +2 more
doaj +1 more source
Outcome-based pricing for new pharmaceuticals via rebates [PDF]
The price of new brand-name prescription drugs has been rising fast in the United States. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year.
Adida, E
core
Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme [PDF]
Aims We investigated the association between worsening renal function (WRF) that occurs during renin–angiotensin–aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared ...
Brenner +21 more
core +1 more source
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein +3 more
wiley +1 more source
A Statistical Model for Stroke Outcome Prediction and Treatment Planning
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit +3 more
core +1 more source

