Results 51 to 60 of about 17,612,218 (346)

Specific gyrA gene mutations predict poor treatment outcome in MDR-TB

open access: yesJournal of Antimicrobial Chemotherapy, 2015
Objectives Mutations in the gyrase genes cause fluoroquinolone resistance in Mycobacterium tuberculosis. However, the predictive value of these markers for clinical outcomes in patients with MDR-TB is unknown to date.
L. Rigouts   +15 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Treatment outcomes and associated factors of stroke in Ethiopia: a systematic review and meta-analysis

open access: yesBMC Cardiovascular Disorders
Introduction Stroke is characterized by a sudden onset of focal or global neurological deficits resulting from reduced cerebral blood flow. Poor treatment outcomes are primarily caused by uncontrolled blood pressure and delayed hospital arrival.
Addisu Getie   +2 more
doaj   +1 more source

Outcome of treatment in patients with methamphetamine poisoning in an Iranian tertiary care referral center

open access: yesJournal of Research in Pharmacy Practice, 2015
Objective: Methamphetamine is the second most widely abused drug worldwide. We performed a study on the treatment outcome of acute methamphetamine intoxication in a referral tertiary care University hospital in Iran.
Parva Paydar   +4 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Treatment and Outcome of Ankle Fractures at the Moi Teaching and Referral Hospital

open access: yesThe Annals of African Surgery, 2014
Background: Ankle fractures are common and protocols for their management are generally well established. Despite this, a significant proportion of the patients get unfavourable outcomes after being managed for this injury.
Kilonzo N   +4 more
doaj  

A comparable study of clinical and optical outcomes after 1.8, 2.0 mm microcoaxial and 3.0 mm coaxial cataract surgery [PDF]

open access: yesInternational Journal of Ophthalmology, 2016
AIM: To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm).
Yi-Bo Yu   +5 more
doaj   +1 more source

Targeting treatment for optimal outcome [PDF]

open access: yesClinical Cardiology, 2000
Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome.
openaire   +3 more sources

Treatment Outcomes in Endodontics [PDF]

open access: yesJournal of Operative Dentistry & Endodontics, 2016
ABSTRACT The success of endodontic treatment has been of great interest to practitioners for many years now. Endodontic failures, which are of particular interest to us, are due to either microbial or nonmicrobial reasons. It is often thought that procedural errors like ledging, perforation, overfilling, underfilling or instrument separation invariably
Ramya Raghu, Raghu Srinivasan
openaire   +1 more source

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