Results 81 to 90 of about 17,612,218 (346)

Satisfaction with orthodontic treatment outcome.

Angle Orthodontist, 2014
OBJECTIVES To examine factors associated with treatment outcome satisfaction in a group of adolescent patients. MATERIALS AND METHODS One hundred and twenty patients (60 girls and 60 boys; mean age, 14.3 years; standard deviation [SD], 1.73 years) were
Ingalill Feldmann
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Treatment of retroauricular keloids: Revision of cases treated at the ENT service of HC/UFPR

International Archives of Otorhinolaryngology, 2012
Introduction: Keloids are benign tumors arising from abnormal healing of the skin, and there are several procedures available for their treatment. Objective: The objective of this study was to evaluate the outcomes of patients undergoing ...
Bettina Carvalho, Annelyse Cristine Ballin, Renata Vecentin Becker, Talita Beithum Ribeiro, Juliana Benthien Cavichiolo, Carlos Roberto Ballin, Marcos Mocellin   +6 more
doaj   +3 more sources

Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report

Clinics
OBJECTIVE: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro. METHODS: Cross-sectional and retrospective study of thirty cases treated over a period of two decades.
Maria de Fátima Borges, Beatriz Hallal Jorge Lara, Janaíne Machado Tomé, Leopoldo Prezia de Araújo, Flávio Cesar Lucas Bugiga, Júlio Cláudio Sousa, Jacqueline Mendes Fonseca Soares, Roberto Alexandre Dezena, Beatriz Pires Ferreira   +8 more
doaj   +1 more source

Treatment outcome of standardized regimen in patients with multidrug resistant tuberculosis

Journal of Pharmacology and Pharmacotherapeutics, 2014
Objective: To evaluate the treatment outcome of second line drugs used in directly observed treatment, short-course (DOTS)-Plus regimen under Revised National Tuberculosis Control Program (RNTCP). Materials and Methods: A prospective, observational study
K. Jain, M. Desai, R. Solanki, R. Dikshit   +3 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

A Case Series on Electrochemotherapy Outcomes in Nine Head and Neck Cancer Patients, Focusing on Symptoms and Tumour Size Reduction [PDF]

International Journal of Anatomy Radiology and Surgery
Introduction: Head and Neck Carcinomas (HNC) are a significant cancer burden in India and worldwide, often necessitating palliative care due to their locoregional relapse.
Pratibha Bharat Sampate, Parag J Watve, Nilesh Dhamne, Chaitanya R Patil, Yogesh Anap   +4 more
doaj   +1 more source

Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan

BMC Infectious Diseases, 2020
Background Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an important indicator for the effectiveness of a national TB control program.
Tauseef Ahmad, Muhammad Ayub Jadoon, Muhammad Khan, Haroon, Muhammad Mumtaz Khan, Akbar Hussain, Taha Hussein Musa, Muhammad Waqar, Eyasu Ejeta, Manoochehr Karami, Kefyalew Addis Alene, Hui Jin   +11 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source