Results 121 to 130 of about 93,603 (306)
This systematic review examined the efficacy of ketamine therapy for treatment resistant depression in the adult population. A conceptual systematic review of the published peer-reviewed literature from the years 2014-2024 was conducted using Boolean ...
Kinney, Christina A.
core
Mirtazapine and Bupropion Combined Treatment in Treatment-resistant Depression
, 2009 Treatment-resistant depression is a difficult problem in clinical practice. Evidence for the efficacy of newer antidepressants, such as duloxetine and bupropion, is not yet well established.
Lai, Chien-Han
core +1 more source
Advanced Science, EarlyView.High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott +5 more
wiley +1 more source
Depression: Can we predict who will relapse?
, 2014 This thesis addresses risk factors and proposed mechanisms to explain relapse to depression. Volume 1 comprises three parts: Part 1 is a literature review consisting of meta-reviews of systematic and non-systematic reviews of studies reporting on risk ...
Buckman, JEJ
core
DBS in Treatment-Resistant Depression
, 2011 IntroductionOf patients with depression, up to 20–30% are treatment-resistant. DBS is being investigated as a novel therapeutic modality that could be effective in this group.Objective and aimsSummary of clinical experience with DBS for treatment ...
C. Zampetaki +3 more
core +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Advanced Science, EarlyView.Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Over 280 million people suffer from depression, which carries a risk of suicide, with up to 30% of those not responding to first-line antidepressant and psychotherapy treatments.
Nichols, Andrew J.
core
Disruption in reciprocal connectivity between the right anterior insula and the left dorsolateral prefrontal cortex is associated with depression and may be a target for neuromodulation.
O’Neil-Kerr, Alexander +17 more
core +1 more source
Advanced Science, EarlyView.A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu +8 more
wiley +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source