Results 121 to 130 of about 8,995,986 (306)
Lexer and Parser Generators in Scheme [PDF]
The implementation of a basic LEX-style lexer generator or YACC-style parser generator requires only textbook knowledge. The im-plementation of practical and useful generators that cooperate well with a specific language, however, requires more ...
Olin Shivers +7 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Increasing water pollution and decreasing energy reserves have emerged as growing concerns for the environment. These pollution are due to the dangerous effects of numerous pollutants on humans and aquatic organisms, such as hydrocarbons, biphenyls ...
Narges Elmi Fard +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Cardiac injury after acute carbon monoxide poisoning and its clinical treatment scheme. [PDF]
Geng S +7 more
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Multiple-bar Nuss operation: an individualized treatment scheme for patients with significantly asymmetric pectus excavatum. [PDF]
Ben XS +11 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
In view of the problem of circulating cooling system blow-down water treatment in a power plant,a scheme to reduce the salt content and sulfate concentration in the circulating cooling system blow-down water was proposed by using nano-filtration ...
NI Bin +5 more
doaj +1 more source

