Results 121 to 130 of about 8,995,986 (306)

Lexer and Parser Generators in Scheme [PDF]

open access: yes, 2004
The implementation of a basic LEX-style lexer generator or YACC-style parser generator requires only textbook knowledge. The im-plementation of practical and useful generators that cooperate well with a specific language, however, requires more ...
Olin Shivers   +7 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A review on development and modification strategies of MOFs Z-scheme heterojunction for photocatalytic wastewater treatment, water splitting, and DFT calculations

open access: yesHeliyon
Increasing water pollution and decreasing energy reserves have emerged as growing concerns for the environment. These pollution are due to the dangerous effects of numerous pollutants on humans and aquatic organisms, such as hydrocarbons, biphenyls ...
Narges Elmi Fard   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Cardiac injury after acute carbon monoxide poisoning and its clinical treatment scheme. [PDF]

open access: yesExp Ther Med, 2020
Geng S   +7 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Multiple-bar Nuss operation: an individualized treatment scheme for patients with significantly asymmetric pectus excavatum. [PDF]

open access: yesJ Thorac Dis, 2020
Ben XS   +11 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Design and comparison of the up-to-standard discharge scheme for blow-down water of circulating cooling system in a power plant

open access: yesGongye shui chuli
In view of the problem of circulating cooling system blow-down water treatment in a power plant,a scheme to reduce the salt content and sulfate concentration in the circulating cooling system blow-down water was proposed by using nano-filtration ...
NI Bin   +5 more
doaj   +1 more source

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