Results 111 to 120 of about 9,833,942 (214)

Taita Taveta County Fiscal Strategy Paper 2014

open access: yes, 2014
The 2014 County Fiscal Strategy Paper is the first of its kind under the devolved system of Governance in Taita Taveta County, which aims at ensuring an effective linkage between policies, planning and budgeting.

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Green Economy Strategy and Implementation Plan 2016-2030: A low carbon, resource efficient, equitable and inclusive socio-economic transformation [PDF]

open access: yes, 2016
The green economy strategy is geared towards enabling Kenya to attain a higher economic growth rate consistent with the vision 2030 which firmly embeds the principles of sustainable development in the overall national growth strategy.

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Development of Intratumoral Drug Delivery Based Strategies for Antitumor Therapy

open access: yesDrug Design, Development and Therapy
Zhimei Jiang,1– 3 Yuzhi Fu,1– 3 Hongxin Shen1– 3 1Department of Pharmacy, West China Second University Hospital of Sichuan University, Chengdu, People’s Republic of China; 2Evidence-Based Pharmacy Center, West China Second University Hospital of Sichuan ...
Jiang Z, Fu Y, Shen H
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

National Wildlife Strategy 2018-2030

open access: yes, 2018
Kenya ranks highly as one of the biodiversity rich country’s in the World. The iconic wildlife and the diverse conservation areas are among the countries most valuable assets.

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National Community Health Digitization Strategy 2020-2025

open access: yes, 2020
Despite its importance, the delivery of community health continues to suffer from weak data collection and reporting tools. This hinders the optimal use of community-level data to inform public health response and resource allocation.

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Neoadjuvant radiation to facilitate surgical treatment of a microcystic adnexal carcinoma with perineural invasion of the vulvar region

open access: yesJAAD Case Reports, 2023
William J. Nahm, BA   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Kenya Health Sector Referral Strategy 2014-2018

open access: yes, 2014
The overall goal of the Kenya Health Sector Referral Strategy is to improve client access to referral. The objectives of the strategy are to realise improved capacity of health providers to identify clients who require referral, develop protocols that ...

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Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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