Results 91 to 100 of about 9,833,942 (214)
The Emerging Role of MicroRNAs in Oral Cancer: From Pathogenesis to Targeted Therapy
Oral cancer remains a major global health problem with high morbidity and mortality rates, and despite advances in therapeutic approaches, challenges persist in early diagnosis and effective disease management.
Mehmet Bugrahan Duz +3 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Strategy for Community Health 2014-2019: Transforming health: Accelerating the attainment of health goals [PDF]
Kenya Vision 2030 emphasizes preventive health care and health promotion to improve health care and reduce the burden of illness in the community. In 2006, the Ministry of Health developed and adopted the community health strategy as a core component of ...
core
Kenya National Energy Efficiency Conservation Strategy and Implementation Plan 2022
The Ministry of Energy partnered with the Copenhagen Centre on Energy Efficiency (CCEE) and other development partners to develop and implement the Kenya National Energy Efficiency and Conservation (KNEECS) Strategy.
core
Overview of Treatment Wetlands; Fundamentals of Treatment Wetlands; Horizontal Flow Wetlands; Vertical Flow Wetlands; French Vertical Flow Wetlands; Intensified and Modified Wetlands; Free Water Surface Wetlands; Other Applications; Additional ...
Molle, Pascal +6 more
core +1 more source
Governance Strategy Paper for Building a Prosperous Kenya 2006 [PDF]
The performance of the Kenyan economy deteriorated markedly in the 1980s and 1990s, with growth falling below its potential. A number of factors contributed to this poor performance, including external shocks and broad-based decline in productivity of ...
core +1 more source
Lactobacillus in autoimmune thyroid diseases: benefit or risk?
Autoimmune thyroid diseases (AITDs), mainly Hashimoto’s thyroiditis and Graves’ disease, are common organ-specific autoimmune disorders driven by complex interactions among genetic susceptibility, immune dysregulation, environmental exposure, and ...
Jin-min Yang +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From gut to brain: pioneering microbial strategies against Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a gradual decline in cognitive abilities and memory loss. Recent studies have indicated that the microbiota-gut-brain axis (MGBA) may be involved in the development of this ...
Jia Wu +5 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

