Results 81 to 90 of about 9,833,942 (214)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Nyamira County Debt Management Strategy Paper 2019

, 2018
The 2019 Nyamira County Government Debt Management Strategy is the fifth to be generated by the County Treasury. This is in line with section 123 of the Public Finance Management Act 2012 which stipulates that on or before the 28th February of each ...

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Territory- and Lesion-Specific Endovascular Strategies in Lower Limb Peripheral Artery Disease: A Cohort Study

Journal of Cardiovascular Development and Disease
(1) Background: Endovascular therapy is widely used for lower limb peripheral artery disease (PAD), yet device performance varies across vascular territories due to anatomical and biomechanical differences.
Thierry Unterseeh, Livio D’Angelo, Mariama Akodad, Youcef Lounes, Hakim Benamer, Benjamin Honton, Antoine Sauguet, Stephane Cook, Mario Togni, Luca Esposito, Gaetano Liccardo, Neila Sayah, Pietro Laforgia, Nicolas Amabile, Thomas Hovasse, Philippe Garot, Antoinette Neylon, Francesca Sanguineti, Stephane Champagne, Ioannis Skalidis   +19 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Traumatic dacryocystitis operated by powered endoscopic dacryocystorhinostomy after orbital fracture reconstruction with an implant: A case report

Indian Journal of Ophthalmology. Case Reports
Traumatic dacryocystitis is a rare complication of nasolacrimal duct obstruction (NLDO) resulting from naso-orbito-ethmoid (NOE) fractures. NLDO following orbital fracture reconstruction using an implant is even less prevalent.
Kerui Wang, Xinyue Yu, Jun Mao, Zuohong Li, Xuanwei Liang   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

National Climate Change Response Strategy 2010 [PDF]

, 2010
In response to the challenges and opportunities posed by climate change, Kenya has developed this National Climate Change Response Strategy. The vision of the Strategy is for a prosperous and climate change resilient Kenya.

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Treatment of restless legs syndrome by acupuncture combined with medicine based on pathophysiological mechanism

Frontiers in Medicine
Restless legs syndrome (RLS) is a neurological disorder characterized by bilateral discomfort in the lower extremities, intense urge to move, and exacerbation of symptoms during the night.
Rujia Liu, Qi Wang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

National Rice Development Strategy 2008-2018 [PDF]

, 2008
This strategy sets the vision, mission, objectives and strategies that Ministry will pursue in ten years with the aim of facilitating growth and development of the rice sub-sector. It will form the basis of which work plans will be formulated at national

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