Results 241 to 250 of about 14,986,124 (359)

Care pathways for people with major depressive disorder: a European Brain Council Value of Treatment study. [PDF]

Eur Psychiatry, 2022
Strawbridge R, McCrone P, Ulrichsen A, Zahn R, Eberhard J, Wasserman D, Brambilla P, Schiena G, Hegerl U, Balazs J, Caldas de Almeida J, Antunes A, Baltzis S, Carli V, Quoidbach V, Boyer P, Young AH.   +16 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Precipitation assessment in wastewater treatment plants operated for biological nutrient removal: A case study in Murcia, Spain

, 2008
R. Barat, A. Bouzas, N. Martí, J. Ferrer, A. Seco   +4 more
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Variations between, and within, jurisdictions in the use of community treatment orders and other compulsory community treatment: study of 402 060 people across four Australian states. [PDF]

BJPsych Open
Kisely S, Bull C, Zirnsak T, Edan V, Gould M, Lawn S, Light E, Maylea C, Newton-Howes G, Ryan CJ, Weller P, Brophy L.   +11 more
europepmc   +1 more source

Diagnosis and treatment of greenstick and torus fractures of the distal radius in children: A prospective randomised single blind study

, 2010
Ippokratis Pountos, J. Clegg, Asim Siddiqui   +2 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A Multicenter Retrospective Study of Avelumab First-Line Maintenance and Subsequent Therapies for Locally Advanced and Metastatic Urothelial Carcinoma: Subgroup Analysis of First-Line Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin, and Gemcitabine Plus Cisplatin in the Japan AVElumab MAintenance and Continuous Treatment Study (JAVEMACS). [PDF]

Curr Oncol
Ikeda M, Fujimoto K, Miura N, Taoka R, Nishihara K, Ikarashi D, Naito S, Shimizu F, Fujihara A, Shono M, Nakagawa T, Kikuchi E.   +11 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

iDiabetes platform-enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in Tayside, Scotland. [PDF]

BMJ Open
Lin Y, Leith D, Abbott M, Barrett R, Bell S, Croudace TJ, Cunningham S, Dillon J, Donnan P, Farre A, Hernández R, Lang C, McKenzie S, Mordi I, Morrow S, Munro C, Philip S, Ryan M, Wake D, Wang H, Win M, Pearson E, iDiabetes Study Team, iDiabetes Study Team.   +23 more
europepmc   +1 more source