Results 71 to 80 of about 14,986,124 (359)

LBA36 Final analysis of RATIONALE-301: Randomized, phase III study of tislelizumab versus sorafenib as first-line treatment for unresectable hepatocellular carcinoma [PDF]

, 2022
Shukui Qin, Masashi Kudo, T Meyer, RS Finn, Peter Vogel, Yibing Bai, Y. Guo, Zhefeng Meng, T. Zhang, Takeshi Satoh, A. Hiraoka, Donatella Marino, Éric Assenat, Lucjan Wyrwicz, Miriam Campos, K. Hsing-Tao, F. Boisserie, Shuang Li, Y. Chen, Andrew X. Zhu   +19 more
openalex   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Psoriatic Arthritis during Treatment with Bevacizumab for Anaplastic Oligodendroglioma

Case Reports in Rheumatology, 2012
Bevacizumab is a recombinant humanised monoclonal antibody directed against the vascular endothelial growth factor (VEGF). The drug, alone or in combination with other anticancer agents, has been shown to be effective against several types of neoplasms ...
D. Graceffa, E. Maiani, A. Pace, F. M. Solivetti, F. Elia, C. De Mutiis, C. Bonifati   +6 more
doaj   +1 more source

The addition of simvastatin administration to cold storage solution of explanted whole liver grafts for facing ischemia/reperfusion injury in an area with a low rate of deceased donation: a monocentric randomized controlled double-blinded phase 2 study

BMC Surgery, 2018
Background Liver transplantation is the best treatment for end-stage liver disease. The interruption of the blood supply to the donor liver during cold storage damages the liver, affecting how well the liver will function after transplant.
Duilio Pagano, Elisabetta Oliva, Simone Khouzam, Fabio Tuzzolino, Davide Cintorino, Sergio Li Petri, Fabrizio di Francesco, Calogero Ricotta, Pasquale Bonsignore, Alessandro Tropea, Sergio Calamia, Federico Costanzo, Angelo Luca, Salvatore Gruttadauria   +13 more
doaj   +1 more source

Public spending for illegal drug and alcohol treatment in hospitals: an EU cross-country comparison [PDF]

, 2014
Background: In view of the current economic crisis and the resulting austerity measures being implemented by governments across Europe, public expenditure for substance abuse treatment has increasingly become a subject of discussion.
Christiaens, Johan, Lievens, Delfine, Vander Laenen, Freya   +2 more
core   +3 more sources

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

The potential for bias in principal causal effect estimation when treatment received depends on a key covariate

, 2011
Motivated by a potential-outcomes perspective, the idea of principal stratification has been widely recognized for its relevance in settings susceptible to posttreatment selection bias such as randomized clinical trials where treatment received can ...
Belin, Thomas R., Zigler, Corwin M.
core   +1 more source

HER2-Low Status Does Not Affect Survival Outcomes of Patients with Metastatic Breast Cancer (MBC) Undergoing First-Line Treatment with Endocrine Therapy plus Palbociclib: Results of a Multicenter, Retrospective Cohort Study [PDF]

, 2022
Francesca Carlino, Anna Diana, Anna Ventriglia, Antonio Piccolo, Carmela Mocerino, Ferdinando Riccardi, Domenico Bilancia, Francesco Giotta, Giulio Antoniol, Vincenzo Famiglietti, S Feliciano, Rodolfo Cangiano, L. LoBianco, Benedetta Pellegrino, Ferdinando De Vita, Fortunato Ciardiello, Michele Orditura   +16 more
openalex   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Longitudinal degradation of the default/salience network axis in symptomatic individuals with elevated amyloid burden.

NeuroImage: Clinical, 2020
Resting-state functional connectivity MRI (rs-fcMRI) is a non-invasive imaging technique that has come into increasing use to understand disrupted neural network function in neuropsychiatric disease.
Aaron P Schultz, Rachel F Buckley, Olivia L Hampton, Matthew R Scott, Michael J Properzi, Cleofé Peña-Gómez, Jeremy J Pruzin, Hyun-Sik Yang, Keith A Johnson, Reisa A Sperling, Jasmeer P Chhatwal   +10 more
doaj   +1 more source