Results 71 to 80 of about 2,574,979 (356)

On the Aα-Spectral Radii of Cactus Graphs

open access: yesMathematics, 2020
Let A ( G ) be the adjacent matrix and D ( G ) the diagonal matrix of the degrees of a graph G, respectively. For 0 ≤ α ≤ 1 , the A α -matrix is the general adjacency and signless Laplacian spectral matrix having the form of
Chunxiang Wang   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

On Trees with a Given Number of Vertices of Fixed Degree and Their Two Bond Incident Degree Indices

open access: yesAxioms
This paper is mainly concerned with the study of two bond incident degree (BID) indices, namely the variable sum exdeg index SEIa and the general zeroth-order Randić index Rα0.
Abeer M. Albalahi   +6 more
doaj   +1 more source

matOptimize: a parallel tree optimization method enables online phylogenetics for SARS-CoV-2 [PDF]

open access: bronze, 2022
Cheng Ye   +8 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Auto-Configuration of ACL Policy in Case of Topology Change in Hybrid SDN

open access: yesIEEE Access, 2016
Software-defined networking (SDN) has emerged as a new network architecture, which decouples both the control and management planes from data plane at forwarding devices.
Rashid Amin   +3 more
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

The Tree of Knowledge: The Biological Roots of Human Understanding

open access: yes, 2007
A review of The Tree of Knowledge: The Biological Roots of Human Understanding, by Humberto R. Maturana and Francisco J. Varela, 1998 [1987]. Revised Edition. Boston and London: Shambhala Publications, 269 pp. ISBN 0877736421. $29.95 USD.
Yves Laberge
semanticscholar   +1 more source

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