Results 221 to 230 of about 1,077,252 (284)

Olympiad-level formal mathematical reasoning with reinforcement learning. [PDF]

open access: yesNature
Hubert T   +38 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

open access: yesAdvanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz   +11 more
wiley   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

open access: yesAdvanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu   +14 more
wiley   +1 more source

The branching structure of trees on directed sets (Combinatorial and Descriptive Set Theory)

open access: yesThe branching structure of trees on directed sets (Combinatorial and Descriptive Set Theory)
openaire  

Pyrodiversity of boreal lake islands begets biodiversity of beetles, plants, and birds. [PDF]

open access: yesEcol Appl
Bell AJ   +5 more
europepmc   +1 more source

New methods drive new biology. [PDF]

open access: yesGenetics
Lohse K, Fields S, Chikina M.
europepmc   +1 more source

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