Results 41 to 50 of about 1,077,252 (284)
On Minimal Tree Realizations of Linear Codes
, 2007 A tree decomposition of the coordinates of a code is a mapping from the coordinate set to the set of vertices of a tree. A tree decomposition can be extended to a tree realization, i.e., a cycle-free realization of the code on the underlying tree, by ...
Kashyap, Navin
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A New Method to Identify Incomplete Frame of Discernment in Evidence Theory
IEEE Access, 2019 One assumption of Dempster-Shafer evidence theory (D-S theory) is the closed world. However, how to determine whether the frame of discernment is incomplete or not is still an open issue.
Renliang Sun, Yong Deng
doaj +1 more source
Data mining of the GAW14 simulated data using rough set theory and tree-based methods [PDF]
BMC Genetics, 2005 Abstract Rough set theory and decision trees are data mining methods used for dealing with vagueness and uncertainty. They have been utilized to unearth hidden patterns in complicated datasets collected for industrial processes. The Genetic Analysis Workshop 14 simulated data were generated using a system that implemented multiple ...
Wei, Liang-Ying +2 more
openaire +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2014 We define the concept of a monotonic theory and show how to build efficient SMT (SAT Modulo Theory) solvers, including effective theory propagation and clause learning, for such theories.
Bayless, Noah +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Evolution: Education and OutreachTree-thinking is a fundamental skill set for understanding evolutionary theory and, thus, part of biological and scientific literacy. Research on this topic is mostly directed towards tree-reading—the umbrella-term for all skills enabling a person to ...
Steven Tyrrell, Philipp Schmiemann
doaj +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source