Results 51 to 60 of about 844,604 (299)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis

BMC Genomics
Background The fundamental way to solve the problems of a Limited interspecific gene pool, poor stress resistance, and low yield in Chinese eucalypt plantations is to use the Heterosis derived from the eucalypt gene pool to select new varieties with rich
Zhiyi Su, Wanhong Lu, Yan Lin, Guo Liu, Anying Huang, Jianzhong Luo   +5 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

From genome to gene expression: the genomic landscape of a hybrid species of Eucalyptus urophylla × Eucalyptus grandis and its divergence from parental species hybrid

BMC Plant Biology
Background Eucalyptus urophylla × Eucalyptus grandis (E. urograndis) is a globally significant forest tree species renowned for its rapid growth, high yield, and exceptional wood production efficiency.
Guo Liu, Jianzhong Luo, Wanhong Lu, Yan Lin, Lei Zhang, Jingyi Pan, Jiangbo Zhai, Anying Huang   +7 more
doaj   +1 more source

Integrated Mitochondrial Genome and Transcriptomic Analyses Reveal Long Non-Coding RNAs Associated with Drought Tolerance in Sophora moorcroftiana

Biology
Sophora moorcroftiana is a perennial deciduous dwarf shrub that exhibits remarkable ecological adaptability, including strong drought resistance on the Tibetan Plateau. In this study, the complete mitogenome of S. moorcroftiana was reported and assembled
Jun Xu, Yan Sun, Yuting Wang, Jibin Nan, Quzhen Gesang, Bingzhang Li   +5 more
doaj   +1 more source

How tree species, tree size, and topographical location influenced tree transpiration in northern boreal forests during the historic 2018 drought [PDF]

, 2021
Jose Gutiérrez López, Pantana Tor‐ngern, Ram Oren, Nataliia Kozii, Hjalmar Laudon, Niles J. Hasselquist   +5 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

The Agroforestry Species Switchboard, a global resource to explore information for 107,269 plant species

Scientific Data
The Agroforestry Species Switchboard is a comprehensive vascular plant database that guides users to information for a particular taxon from a global but fragmented set of resources.
Roeland Kindt, Ilyas Siddique, Ian Dawson, Innocent John, Fabio Pedercini, Jens-Peter Lillesø, Lars Graudal   +6 more
doaj   +1 more source

Genetic diversity of avocado (Persea americana Mill.) germplasm using pooled sequencing

BMC Genomics, 2019
Background Discovering a genome-wide set of avocado (Persea americana Mill.) single nucleotide polymorphisms and characterizing the diversity of germplasm collection is a powerful tool for breeding.
Mor Rubinstein, Ravit Eshed, Ada Rozen, Tali Zviran, David N. Kuhn, Vered Irihimovitch, Amir Sherman, Ron Ophir   +7 more
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source