Results 191 to 200 of about 99,833 (289)

Metabolic improvement in patients with acid sphingomyelinase deficiency following intravenous trehalose administration: an untargeted pharmacometabolomic study. [PDF]

Orphanet J Rare Dis
Khoshakhlagh M, Hasanpour M, Iranshahi M, Asili J, Tasbandi A, Jamialahmadi T, Sahebkar A, Iranshahy M.   +7 more
europepmc   +1 more source

Gene Expression Patterns Regulating Peanut Reproductive Phenology

Plant Direct, Volume 10, Issue 5, May 2026.
ABSTRACT Peanut reproduction is foundational for crop yield, breeding, and evolution. However, gene regulation underlying peanut flowering pattern and timing has received limited attention. Cultivated peanut (Arachis hypogaea L.) shows two distinct flowering patterns between two subspecies, with ssp.
Carlos Henrique Cardon, Adnan Kivanc Corut, Ye Chu, Jason Wallace, Ran Hovav, Peggy Ozias‐Akins   +5 more
wiley   +1 more source

Enhanced ganoderic acids production by using thermotolerant Ganoderma tsugae at high-temperature liquid cultivation. [PDF]

PLoS One
Ma Q, Jing YM, Luo LY, He XL, Liu YQ.
europepmc   +1 more source

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

Small, Volume 22, Issue 26, 8 May 2026.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi, Haikun Liu, Ahmed Refaat, Hung Nguyen, Anne Nguyen, Kaiting Miao, Yuyang Song, Sylvain Trépout, Rico F. Tabor, Liliana de Campo, Karlheinz Peter, Mark Louis P. Vidallon, Xiaowei Wang   +12 more
wiley   +1 more source

Commentary: Trehalose alleviates nephropathy in focal segmental glomerulosclerosis via the upregulation of the WT-1/EZH2 pathway. [PDF]

Front Pharmacol
Tian F.
europepmc   +1 more source

Molecular Detection and Antibiotic Susceptibility Profiling of Mannheimia haemolytica Isolates From Pneumonic Pasteurellosis Suspected Cases of Sheep in Northwestern Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study in Northwestern Ethiopia analysed M. haemolytica in pneumonic sheep and identified 23 M. haemolytica isolates from 140 nasal swab samples. M. haemolytica isolates were sensitive to most drugs, including tetracycline, chloramphenicol, gentamicin, streptomycin, kanamycin and ampicillin.
Fanuel Bizuayehu Yihunie, Saddam Mohammed Ibrahim, Destaw Asfaw Ali, Mequanint Addisu Belete, Teshager Dubie, Zemenu Bitew, Takele Abayneh   +6 more
wiley   +1 more source

Exometabolome variation in the fungal pathogen of humans <i>Candida albicans</i> reveals specificities at the genetic clade and strain levels. [PDF]

Appl Environ Microbiol
Alaban LR, Bunescu A, Abi-Ghanem J, Bequet F, Lebrat J, Tulinski P, Kosmala D, Bougnoux M-E, d'Enfert C, Thomas V.   +9 more
europepmc   +1 more source

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

Acta Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami, Domenico Marson, Eiki Yamashita, Bruno Broshka, Ui Okada, Maho Aoki, Giannamaria Annunziato, Erik Laurini, Emanuele Carosati, Marco Pieroni   +9 more
wiley   +1 more source

Impact of the Addition of Disaccharides on the Encapsulation of Chokeberry Polyphenols on Rice and Pea Proteins. [PDF]

Molecules
Kopjar M, Buljeta I, Pichler D, Krezić J, Nedić Tiban N, Pichler A.   +5 more
europepmc   +1 more source

Effects of fermentation time and sugar type on the processing characteristics and quality of special low-protein steamed sponge cakes. [PDF]

Food Chem X
Zi Y, Shi C, Liu Z, Cai W, Zhong J.
europepmc   +1 more source