Prevalence of genetically determined trehalase deficiency in populations of Siberia and Russian Far East [PDF]
International Journal of Circumpolar Health, 2023 In order to be digested, the disaccharide trehalose needs to be cleaved by the trehalase enzyme. There were reports suggesting that trehalase deficiency was more common in high-latitude than in the temperate climate populations.
Andrey Kozlov +5 more
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Trehalase localization in the cerebral cortex, hippocampus and cerebellum of mouse brains
Journal of Advanced Research, 2019 The non-reducing disaccharide trehalose is biosynthesized in several species but not in vertebrates. However, trehalase, the enzyme required for its cleavage, has been observed in different mammalian organs.
L. Halbe, A. Rami
exaly +3 more sources
Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication. [PDF]
PLoS PathogensTrehalose is a non-reducing disaccharide that is the major sugar found in insect hemolymph fluid. Trehalose provides energy, and promotes growth, metamorphosis, stress recovery, chitin synthesis, and insect flight.
Andrew D Marten +8 more
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The Evolutionary History and Functional Divergence of Trehalase (treh) Genes in Insects
Frontiers in Physiology, 2019 Trehalases (treh) have been found in different organisms, such as bacteria, fungi, yeast, nematodes, insects, vertebrates, and plants. Their biochemical properties are extremely variable and not yet fully understood.
Matteo Vecchi +2 more
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Validamycin Inhibits the Reproductive Capacity of Spodoptera frugiperda (Lepidoptera: Noctuidae) by Suppressing the Activity of Trehalase [PDF]
InsectsSpodoptera frugiperda (J. E. Smith, 1797), an omnivorous crop pest worldwide, reproduces prolifically. Validamycin, a competitive natural inhibitor of trehalase, is regarded as an effective and safe insecticide.
Fan Zhong +8 more
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New Frontiers on Human Safe Insecticides and Fungicides: An Opinion on Trehalase Inhibitors
Molecules, 2020 In the era of green economy, trehalase inhibitors represent a valuable chance to develop non-toxic pesticides, being hydrophilic compounds that do not persist in the environment. The lesson on this topic that we learned from the past can be of great help
Camilla Matassini +2 more
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Physiological Response of Tribolium castaneum to CO2 Controlled Atmosphere Stress Under Trehalose Feeding [PDF]
InsectsThis study investigated the physiological regulatory mechanisms by which exogenous trehalose intake enhances the adaptation of the global stored-grain pest T. castaneum to high-concentration carbon dioxide (CO2) stress.
Yuya Zhang +7 more
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Effects of Trehalase on the Gene Expression of the Reproductive Regulation Pathway Network and Triglyceride Metabolism in Nilaparvata lugens (Stål) [PDF]
InsectsThe high reproductive performance of Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is one of the key factors contributing to its serious damage. Studies have demonstrated that trehalose hydrolysis, catalyzed by trehalase (TRE), plays an important ...
Bin Tang +7 more
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Assessing the efficacy of the natural disaccharide trehalose in ameliorating diet-induced obesity and metabolic dysfunction [PDF]
Frontiers in NutritionTrehalose is a naturally occurring disaccharide with versatile commercial applications and health benefits, including promise as a therapeutic for obesity and diabetes.
Yu-Sheng Yeh +18 more
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Peroxiredoxin Tsa1 Regulates the Activity of Trehalose Metabolism‐Related Enzymes During Wine Yeast Biomass Propagation [PDF]
Microbial BiotechnologyTrehalose metabolism plays a crucial role in yeast stress tolerance during biomass propagation and dehydration, but its regulatory mechanisms under these industrial conditions remain incompletely understood. This study analyses the role of an antioxidant
Víctor Garrigós +3 more
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