Results 31 to 40 of about 290 (115)

Induction of Trehalase in Arabidopsis Plants Infected With the Trehalose-Producing Pathogen Plasmodiophora brassicae

Molecular Plant-Microbe Interactions, 2002
Various microorganisms produce the disaccharide trehalose during their symbiotic and pathogenic interactions with plants. Trehalose has strong effects on plant metabolism and growth; therefore, we became interested to study its possible role in the ...
David Brodmann, Astrid Schuller, Jutta Ludwig-Müller, Roger A. Aeschbacher, Andres Wiemken, Thomas Boller, Astrid Wingler   +6 more
doaj   +1 more source

Lack of Functional Trehalase Activity in Candida parapsilosis Increases Susceptibility to Itraconazole

Journal of Fungi, 2022
Central metabolic pathways may play a major role in the virulence of pathogenic fungi. Here, we have investigated the susceptibility of a Candida parapsilosis mutant deficient in trehalase activity (atc1Δ/ntc1Δ strain) to the azolic compounds fluconazole
Ruth Sánchez-Fresneda, María Luz Muñoz-Megías, Genoveva Yagüe, Francisco Solano, Sergi Maicas, Juan Carlos Argüelles   +5 more
doaj   +1 more source

Screening and characterization of food-derived trehalase inhibitors

Food Science and Human Wellness
Trehalose is an autophagy-promoting disaccharide, which can improve and delay chronic diseases like neurodegenerative diseases and atherosclerosis, but its bioavailability is severely restricted by endogenous trehalase in mammals.
Yanmei Zhang, Lianghua Lu, Qingyan Wang, Xiaoming Li, Di Lu, Ribo Huang, Chenghua Wang   +6 more
doaj   +1 more source

Validamycin Inhibits the Synthesis and Metabolism of Trehalose and Chitin in the Oriental Fruit Fly, Bactrocera dorsalis (Hendel)

Insects, 2023
The oriental fruit fly, Bactrocera dorsalis (Hendel), is a notorious invasive pest that has raised concerns worldwide. Validamycin has been demonstrated to be a very strong inhibitor against trehalase in a variety of organisms.
Ying Li, Yonghong Xu, Shunjiao Wu, Baohe Wang, Yaying Li, Yinghong Liu, Jia Wang   +6 more
doaj   +1 more source

Biosynthesis of the Trehalase Inhibitor Trehazolin.

The Journal of Antibiotics, 2002
Trehazolin (1) is a trehalase inhibitor produced by Micromonospora coriacea. Biosynthesis of 1 was studied by feeding experiments with a variety of labeled precursors. Feeding experiments with [1-13C]- and [6-13C]-D-glucose revealed that the carbon skeletons of both a glucose residue and a cyclopentane ring moiety in 1 were each derived from glucose ...
Yasumasa, Sugiyama, Hiromichi, Nagasawa, Akinori, Suzuki, Shohei, Sakuda   +3 more
openaire   +3 more sources

Evaluation of the Expression and Function of the TRE2-like and TRE2 Genes in Ecdysis of Harmonia axyridis

Frontiers in Physiology, 2019
Harmonia axyridis is an important predatory insect and widely used in biological control of agricultural and forestry pests. Trehalose is directly involved in the energy storage of the H.
Yan Li, Xu Chen, Sha-Sha Wang, Bi-Ying Pan, Shi-Gui Wang, Su Wang, Bin Tang   +6 more
doaj   +1 more source

Identification of natural inhibitors targeting trehalase of Anopheles funestus in the management of malaria: A Biocomputational assessment

Journal of Vector Borne Diseases
Background & objectives: Anopheles funestus is playing an increasingly important role in malaria transmission in sub-Saharan Africa. Trehalase, an enzyme required for trehalose breakdown, is important for mosquito flight and stress adaptation. Hence, its
Amer Al Ali, Abdulaziz Asiri, Mohammed H Abu-Alghayth, Maryam Musleh Althobiti, Bandar Ali Al Hader, Zain Alhindi   +5 more
doaj   +1 more source

Comparison of gut morphology and distribution of trehalase activity in the gut of wood-feeding and fungus-growing termites (Isoptera: Termitidae)

European Journal of Entomology, 2017
Termites are important decomposer due to their ability to digest cellulose and their diverse feeding habits. Trehalase is an enzyme that hydrolyzes trehalose to glucose in insects and has an important biological role.
Nujira TATUN, Chutamas SAWATNATHI, Suwakan TANSAY, Jatuporn TUNGJITWITAYAKUL   +3 more
doaj   +1 more source

The involvement of the Candida glabrata trehalase enzymes in stress resistance and gut colonization

Virulence, 2021
Candida glabrata is an opportunistic human fungal pathogen and is frequently present in the human microbiome. It has a high relative resistance to environmental stresses and several antifungal drugs.
Mieke Van Ende, Bea Timmermans, Giel Vanreppelen, Sofía Siscar-Lewin, Daniel Fischer, Stefanie Wijnants, Celia Lobo Romero, Saleh Yazdani, Ona Rogiers, Liesbeth Demuyser, Griet Van Zeebroeck, Yuke Cen, Karl Kuchler, Sascha Brunke, Patrick Van Dijck   +14 more
doaj   +1 more source

Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication.

PLoS Pathogens
Trehalose is a non-reducing disaccharide that is the major sugar found in insect hemolymph fluid. Trehalose provides energy, and promotes growth, metamorphosis, stress recovery, chitin synthesis, and insect flight.
Andrew D Marten, Douglas P Haslitt, Chad A Martin, Akshitha Karthikeyan, Daniel H Swanson, Karishma Kalera, Ulysses G Johnson, Benjamin M Swarts, Michael J Conway   +8 more
doaj   +1 more source