Trehalase Inhibitor Validamycin May Have Additional Mechanisms of Toxicology against Rhizoctonia cerealis [PDF]
Journal of Fungi, 2023 Sharp eyespot is a crucial disease affecting cereal plants, such as bread wheat (Triticum aestivum) and barley (Hordeum vulgare), and is primarily caused by the pathogenic fungus Rhizoctonia cerealis.
Xiaoyue Yang +9 more
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New Frontiers on Human Safe Insecticides and Fungicides: An Opinion on Trehalase Inhibitors
Molecules, 2020 In the era of green economy, trehalase inhibitors represent a valuable chance to develop non-toxic pesticides, being hydrophilic compounds that do not persist in the environment. The lesson on this topic that we learned from the past can be of great help
, Francesca Cardona, Camilla Matassini
exaly +3 more sources
Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors [PDF]
Molecules, 2018 This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides.
Giampiero D’Adamio +7 more
doaj +2 more sources
Validamycin Inhibits the Reproductive Capacity of Spodoptera frugiperda (Lepidoptera: Noctuidae) by Suppressing the Activity of Trehalase [PDF]
InsectsSpodoptera frugiperda (J. E. Smith, 1797), an omnivorous crop pest worldwide, reproduces prolifically. Validamycin, a competitive natural inhibitor of trehalase, is regarded as an effective and safe insecticide.
Fan Zhong +8 more
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Effects of Trehalase on the Gene Expression of the Reproductive Regulation Pathway Network and Triglyceride Metabolism in Nilaparvata lugens (Stål) [PDF]
InsectsThe high reproductive performance of Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is one of the key factors contributing to its serious damage. Studies have demonstrated that trehalose hydrolysis, catalyzed by trehalase (TRE), plays an important ...
Bin Tang +7 more
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Physiological Response of Tribolium castaneum to CO2 Controlled Atmosphere Stress Under Trehalose Feeding [PDF]
InsectsThis study investigated the physiological regulatory mechanisms by which exogenous trehalose intake enhances the adaptation of the global stored-grain pest T. castaneum to high-concentration carbon dioxide (CO2) stress.
Yuya Zhang +7 more
doaj +2 more sources
Identification of natural inhibitors targeting trehalase of Anopheles funestus in the management of malaria: A Biocomputational assessment [PDF]
Journal of Vector Borne DiseasesBackground & objectives: Anopheles funestus is playing an increasingly important role in malaria transmission in sub-Saharan Africa. Trehalase, an enzyme required for trehalose breakdown, is important for mosquito flight and stress adaptation. Hence, its
Amer Al Ali +5 more
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The Enigma of NTH2 Gene in Yeasts [PDF]
MicroorganismsThe enzymatic hydrolysis of the non-reducing disaccharide trehalose in yeasts is carried out by trehalase, a highly specific α–glucosidase. Two types of such trehalase activity are present in yeasts, and are referred to as neutral and acid enzymes.
Sergi Maicas +3 more
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Assessing the efficacy of the natural disaccharide trehalose in ameliorating diet-induced obesity and metabolic dysfunction [PDF]
Frontiers in NutritionTrehalose is a naturally occurring disaccharide with versatile commercial applications and health benefits, including promise as a therapeutic for obesity and diabetes.
Yu-Sheng Yeh +18 more
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Trealose e trealase em tenebrio molitor L Trehalose and Trehalase in Tenebrio molitor L [PDF]
Memorias do Instituto Oswaldo Cruz, 1972 Foi estudada a concentração em trealose e a atividade em trealase do Tenebrio molitor L. durante as tres fases da metamorfose (larva, ninfa, imago). Verificou-se que na larva e no adulto os valores são mais elevados conforme a curva da fig. 3. A trealose
Cristina Piedras Lopes, Gilberto Villela
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