Results 91 to 100 of about 284,386 (244)

Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome

Arthritis &Rheumatology, EarlyView.
Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani, Tatsuma Ban, Yohei Kirino, Go R. Sato, Soichiro Adachi, Yuki Iizuka, Kayo Harita, Ayaka Maeda, Osamu Ohara, Hideaki Nakajima, Tomohiko Tamura   +10 more
wiley   +1 more source

Multi-trench Fiber for high power laser applications

, 2014
Optical fibers have realized their immense potential for high power applications in the last decade. However, non-linearity still remains a challenge for power scaling for fiber lasers [1].
Jain, D., May-Smith, T.C., Sahu, J.K.
core   +1 more source

An epidemiological study of Pediculus capitis in students of Pakdasht county, in autumn of 2013

پژوهان, 2015
Introduction: Despite progress in health, human lice are still considered as a health problem. Lice could transmit different diseases to human such as epidemic relapsing fever, epidemic typhus and trench fever.
Behroz Davari, Mohsen Kolivand, Ali Poomohammadi, Ali Faramarzi Gohar, Fariba Feizei, Somayeh Rafat Bakhsh, Samaneh Ahmadi   +6 more
doaj  

A man of his time: Joseph Leidy, racial science, and American anatomy

Anatomical Sciences Education, EarlyView.
Abstract Professor Joseph Leidy M.D. was arguably the most influential anatomist in the nineteenth‐century United States, having written over 500 publications and serving as the first President of the Association of American Anatomists. While many of Leidy's diverse contributions to American science and medicine are well‐known, scholars have said much ...
Christopher D. E. Willoughby
wiley   +1 more source

Low heat flow from young oceanic lithosphere at the Middle America Trench off Mexico

, 2005
Seismic reflection profiles across the Middle America Trench at 20°N show a high amplitude bottom simulating reflector interpreted as marking a phase transition between methane hydrate and free gas in the pore space of both accreted and trench sediments.
Bartolome, R., Dañobeitia, Juan José, Byrne, S., Minshull, T.A., Danobeitia, J., Byrne, Siobhán, Minshull, Timothy A., Bartolomé, Rafael   +7 more
core   +1 more source

Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever. [PDF]

, 2014
The host-pathogen interactions induced by Salmonella Typhi and Salmonella Paratyphi A during enteric fever are poorly understood. This knowledge gap, and the human restricted nature of these bacteria, limit our understanding of the disease and impede the
Thanh, TH, Elin Näsström, Ha Thanh, T, Baker, S, Dolecek, Christiane, Antti, H, Karkey, A, Voong Vinh, P, Thieu, Nga Tran Vu, Stephen Baker, Vinh, Phat Voong, Thieu, NTV, Amit Arjyal, Vinh, PV, Näsström, E, Thwaites, Guy, Vu Thieu, Nga Tran, Anders Johansson, Thwaites, G, Antti, Henrik, Guy Thwaites, Johansson, A, Arjyal, A, Karkey, Abhilasha, Ha Thanh, Tuyen, Buddha Basnyat, Vu Thieu, NT, Basnyat, B, Basnyat, Buddha, Arjyal, Amit, Sabina Dongol, Abhilasha Karkey, Johansson, Anders, Tuyen Ha Thanh, Henrik Antti, Näsström, Elin,, Phat Voong Vinh, Dongol, S, Voong Vinh, Phat, Thanh, Tuyen Ha, Johansson, Anders,, Dongol, Sabina, Nga Tran Vu Thieu, Dolecek, C, Näsström, Elin, Antti, Henrik,, Baker, Stephen, Christiane Dolecek   +47 more
core   +1 more source

Clinical and Genetic Factors Associated With Regression in Children With Autism Spectrum Disorders

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with complex genetic and environmental underpinnings. A clinically significant subset of children with ASD experience developmental regression (regASD), characterized by the acute loss of previously acquired skills. The mechanisms, predictors, and molecular basis of
Anna Maruani, Emma Delclaud, Paul Bruzeau, Richard Delorme, Anne‐Claude Tabet, Valérie Vantalon, Jonathan Levy, Pierre Ellul   +7 more
wiley   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Drug fever

, 2012
[Extract] INTRODUCTION — Clinicians are universally aware of the common occurrence of fever caused by drugs, although reliable data on incidence are not available. Fever can be the sole manifestation of an adverse drug reaction in 3 to 5 percent of cases
Sexton, Daniel J., McDonald, Malcolm
core   +1 more source

Mapping the tRNA modification landscape of Bartonella henselae Houston I and Bartonella quintana Toulouse

Frontiers in Microbiology
Transfer RNA (tRNA) modifications play a crucial role in maintaining translational fidelity and efficiency, and they may function as regulatory elements in stress response and virulence.
Samia Quaiyum, Jingjing Sun, Jingjing Sun, Virginie Marchand, Guangxin Sun, Colbie J. Reed, Yuri Motorin, Peter C. Dedon, Peter C. Dedon, Michael F. Minnick, Valérie de Crécy-Lagard, Valérie de Crécy-Lagard   +11 more
doaj   +1 more source