Results 41 to 50 of about 20,847 (278)

The Passenger Domain of Bartonella bacilliformis BafA Promotes Endothelial Cell Angiogenesis via the VEGF Receptor Signaling Pathway

open access: yesmSphere, 2022
Bartonella bacilliformis is a Gram-negative bacterial pathogen that provokes pathological angiogenesis and causes Carrion’s disease, a neglected tropical disease restricted to South America. Little is known about how B.
Kentaro Tsukamoto   +4 more
doaj   +1 more source

Liverpool Corporation and the origins of municipal social housing, 1842–1890 [PDF]

open access: yes, 2016
This article addresses the improvements made to the housing and sanitation conditions of Liverpool’s working-class poor through a series of municipal initiatives between 1842 and 1890.
Dockerill, Bertie
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Risk Factors for Bartonella species Infection in Blood Donors from Southeast Brazil. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Bacteria from the genus Bartonella are emerging blood-borne bacteria, capable of causing long-lasting infection in marine and terrestrial mammals, including humans.
Pedro Paulo Vissotto de Paiva Diniz   +8 more
doaj   +1 more source

From Enlistment to the Grave: The Impact of the First World War on 52 Canadian Soldiers [PDF]

open access: yes, 2012
Because they have clearly demarcated beginnings and endings, wars tend to be studied in isolation. Studies are made of the events leading up to wars, the wars themselves, and their aftermaths as though each could be easily pigeon-holed.
Wert, Mike
core   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Endocarditis caused by Bartonella Quintana, a rare case in the United States

open access: yesIDCases, 2019
Bartonella quintana is a relatively rare cause of endocarditis in the United States (USA). Historically it was linked with trench fever, but cardiac involvement seems to be more prevalent recently.
Mahsa Mohammadian, Saira Butt
doaj   +1 more source

Journal of another plague year [PDF]

open access: yes, 2009
Recent years have seen a catalogue of plagues and sundry other contagions. Hard on the scaly heels of avian flu follows global warming, swine flu, obesity, and now the economic plague. This litany of woes has affect’d me deeply, as these few entries from
Morrison, D., Petticrew, M.
core   +2 more sources

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

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