Results 231 to 240 of about 3,342,431 (305)

Impact of an integrated electronic Clinical Decision Support System with proactive Antimicrobial Stewardship Feedback on prescribing appropriateness: a 2-year single-centre time-series analysis. [PDF]

JAC Antimicrob Resist
Meschiari M, Onorato L, Albertini M, Fontana B, Menozzi V, Cantergiani S, Simion M, Santoro A, Franceschini E, Orlando G, Casolari S, Cervo A, Menozzi M, Bedini A, Beghetto B, Nardini G, Roncaglia E, Sarti M, Baldi J, Cancian L, Casini S, Mussini C.   +21 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Knowledge graph-guided multiple sclerosis identification and therapeutic trend analysis: Real-world evidence from two large healthcare systems. [PDF]

PLOS Digit Health
Gan Z, Zhu W, Tang W, Sweet SM, Morris M, Han Y, Chen C, Lu J, Song E, Moro M, Visweswaran S, Cai T, Chitnis T, Cai T, Xia Z.   +14 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Hemispheric asymmetry in evapotranspiration reveals terrestrial water-flux redistribution. [PDF]

Sci Adv
Zhang Y, Li C, Kong D, Xu Z, Miralles D, McVicar TR, Tian J, Zhang X, Ma N, Li X, Zhang Y, Wei H, Zhao G, Xia J, Huang Y, Ai Z, Tang R, Sun G, Uhlenbrook S, Destouni G.   +19 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Eksekutif : Juli - Desember 2004

, 2005
Trend media
core  

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis. [PDF]

Addiction
McAdam E, Karamouzian M, Milloy MJ, Verdicchio C, Sayre EC, Hayashi K, Kerr T, DeBeck K.   +7 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Shift of antibiotic resistance after the COVID-19 pandemic: results from the INVIFAR Network. [PDF]

JAC Antimicrob Resist
Garza-González E, Rojas-Larios F, Vázquez-Larios MDR, Hernández-Durán M, Feliciano-Guzman JM, Mireles-Davalos CD, Martínez-Guerra BA, Gomez-Quiroz A, Aguirre-Torres JA, Mena-Ramírez JP, Barlandas-Rendón NRE, Treviño-Rangel RJ, Choy-Chang EV, Jaime-Sánchez JL, Bolado-Martínez E, Avilés-Benítez LK, Couoh-May CA, López-Gutiérrez E, Hernandez-Martinez J, Hernandez-Cordova IY, Silva-Gamiño AR, Garcia-Estrada KC, Rincón-Zuno J, Gil-Veloz M, López-Ovilla I, Morales-de-la-Peña CT, Tirado-Morales LJ, Arauz-Cabrera JI, López-Moreno LI, Jacobo-Baca G, Huerta-Baltazar CR, Rodríguez-Muñoz L, Ortiz-Porcayo AE, Padilla-Ibarra C, López-Vázquez AD, Gutiérrez-Brito M, Valenzuela-Oroz A, Quevedo-Ramos MA, López-García M, Torres-Barajas CE, Hernández-Guillén E, Martínez-Lazo FA, García-Ortega VAA, Dorado-Del-Rio M, Castillo-Jacome A, Solis-Hernandez JE, Ballesteros-Monrreal MG, Clemente-Callejas ZL, Franco-Cendejas R, López-Jácome LE.   +49 more
europepmc   +1 more source