Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Socioeconomic inequalities in type 2 diabetes comorbidities in different population subgroups: trend analyses using German health insurance data. [PDF]
Sci Rep, 2023 Safieddine B +4 more
europepmc +1 more source
Re-examining Husserl’s Non-Conceptualism in the Logical Investigations [PDF]
, 2019 A recent trend in Husserl scholarship takes the Logische Untersuchungen (LU) as advancing an inconsistent and confused view of the non-conceptual content of perceptual experience.
Kidd, Chad
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Exploring Self-efficacy for Condom Use in Spanish People: A Trend Analyses by Gender from 2004 to 2020. [PDF]
AIDS Behav, 2023 Giménez-García C +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Impact of Trend Analysis On Quality Of Finished Products In A Pharmaceutical Industry
UMYU Journal of Microbiology Research, 2019 In this study, trend analyses were carried out on the results obtained for microbiology purity tests and assay of 25 batches of Paracetamol Syrup obtained from a selected Pharmaceutical Industry within Minna Metropolis using the 3-Sigma Method.
Orukotan, A. A., Oloninefa, S. D.
doaj +1 more source
Slow Trends - A Problem in Analysing Pupil Dynamics
Proceedings of the 2nd International Conference on Physiological Computing Systems, 2015 As of recently, research efforts are intensified to operationalize pupil dynamics for cognitive and affective classification in human-machine interaction. However, signal analysis of pupil diameter changes is problematic since the respective dynamics consist of three essential components that have to be disentangled: Very slow diameter changes, slow ...
Strauch, Christoph +3 more
openaire +2 more sources
The Effects of Changing Technology: The Impacts of a Changing Cost Structure on Land Tenure Arrangements in the Mississippi Delta, 1996 - 2004 [PDF]
Genetically modified (GM) cotton varieties have changed many aspects of cotton production in the United States. The advent of GM varieties has fueled the ongoing trend of increasing farm size and fewer farmers.
Anderson, John D. +3 more
core +1 more source
, 2013 There are a wide variety of scientific contribution rating indices including the impact factor and h-index. These are used for quantitative analyses on research papers published in the past, and therefore unable to incorporate in the assessment the ...
Kawamura, Masayoshi, Otsuki, Akira
core +1 more source