The Impact of Improved Population Life Expectancy in Survival Trend Analyses of Specific Diseases. [PDF]
Health Serv Res, 2016 van Walraven C.
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Child undernutrition in Kenya: trend analyses from 1993 to 2008-09. [PDF]
BMC Pediatr, 2014 Matanda DJ, Mittelmark MB, Kigaru DM.
europepmc +1 more source
Bibliometric analyses on repository contents as a library service for the evaluation of research [PDF]
Since the last two decennia, the library of Wageningen University and Research (or Wageningen UR) has been involved in several bibliometric analyses for the evaluation of scientific output of staff, chair groups, research institutes and graduate schools.
Gerritsma, W., Veller, M.G.P., van
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Trend analyses of insulin delivery systems in the United States. [PDF]
J Diabetes Sci Technol, 2011 Lee LJ, Li Q, Reynolds MW, Engelman W.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Multilevel and spatial-time trend analyses of the prevalence of hypertension in a large urban city in the USA. [PDF]
J Urban Health, 2013 Liu L +5 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A combination of cross correlation and trend analyses reveals that Kawasaki disease is a pollen-induced delayed-type hyper-sensitivity disease. [PDF]
Int J Environ Res Public Health, 2014 Awaya A, Nishimura C.
europepmc +1 more source