Results 241 to 250 of about 30,405,915 (378)

Combined Burden of Preterm and Low Birthweight Births in Greece: A Nationwide Time-Trend Analysis. [PDF]

Cureus
Vlachadis N, Sioutis D, Christodoulaki C, Machairiotis N, Theofanakis C, Louis K, Panagopoulos P.   +6 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Increasing Rates of Capsular Repair in Pediatric Hip Arthroscopy: A Trend Analysis between 2014 and 2022. [PDF]

Hip Pelvis
Geffken SJ, Bartlett L, Sacklow J, Tharakan S, Klein B, Cohn RM.   +5 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Trend analysis and prediction of fabric tear performance testing processes based on the BLTT-FT model. [PDF]

PLoS One
Jiao Q, Zhang Y, Lu Y, He B, Zhu M, Wang K.   +5 more
europepmc   +1 more source

Regional aspects of the recent observed trends in the Western Mediterranean: Insights from a Timescale Decomposition Analysis [PDF]

Diego Campos, Matías Olmo, Pep Cos, Ángel G. Muñoz, Francisco J. Doblas‐Reyes   +4 more
openalex   +1 more source

Market Analysis: New Trends in Surgery and Anesthesia, October 17-18, 2020 | Vancouver, Canada [PDF]

, 2020
Espeed Khoshbin
openalex  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Temporal trends of no moderate to vigorous physical activity in adolescents: a 16-year trend analysis of 115,926 participants. [PDF]

Int J Behav Nutr Phys Act
Chen S, Brown D, Pfledderer CD, Huang WY, Tremblay MS.   +4 more
europepmc   +1 more source