Results 261 to 270 of about 30,405,915 (378)

Global, regional, and national burdens of pruritus in children and adolescents aged under 20 years from 1990 to 2021: a trend analysis. [PDF]

Front Med (Lausanne)
Ding X, Yang Z, Lu H, Chen B.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Trend analysis and future projections of global burden of opioid use disorder (OUD) from 1990 to 2030. [PDF]

Front Pharmacol
Jiang W, Zhao Z, Zhu B.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Rising Deaths due to Malnutrition and Growing Disparities in the U.S.: A 24-Year Trend Analysis From 1999 and 2023. [PDF]

Food Sci Nutr
Rath S, Ishaque G, Ur Rahman S, Sanan A, Syed B, Ali M, Kumari P, Lal A.   +7 more
europepmc   +1 more source

The trend of drone in logistics: Document analysis [PDF]

, 2015
Nizamuddin Zainuddin, Keen Ann Ng, Wai Huat Fong, Woei Shuoh Wang   +3 more
openalex  

Variability and time series trend analysis of rainfall and temperature in northcentral Ethiopia: A case study in Woleka sub-basin

, 2017
Amogne Asfaw, B. Simane, Ali Hassen, A. Bantider   +3 more
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Exploring non-target screening variability in unsupervised multivariate time trend analysis of LC-HRMS data. [PDF]

Anal Bioanal Chem
Armin R, Vosough M, Schmidt TC.
europepmc   +1 more source

A Bibliometric Analysis of Research Trends in Herbal Medicine for Periodontal Disease

Simin Li, Deborah Kreher, Gerhard Schmalz   +2 more
openalex   +2 more sources