Results 271 to 280 of about 30,405,915 (378)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Machine-Learning-Based Fatigue Trend Analysis on IMU Wearable Sensor Data from Construction Site Workers. [PDF]
Sensors (Basel)Keränen JS +7 more
europepmc +1 more source
Has the Covid-19 pandemic altered the frequency of periodontitis? An analysis conducted using Google Trends. [PDF]
Devrim Deniz Üner, Bozan Serhat İzol
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Incidence of Dementia in Canada: A National Trend Analysis of Newly Diagnosed Cases. [PDF]
CureusFasoro OS +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Severity-dependent benefits of AI-assisted 3D planning in total hip arthroplasty: a Crowe I-IV subgroup and trend analysis. [PDF]
BMC Musculoskelet DisordLu Z +12 more
europepmc +1 more source