Results 161 to 170 of about 6,114,826 (359)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Spatially refined satellite gravimetry captures human signatures in global terrestrial water storage trends. [PDF]
O'Neill MM, Rodell M, Loomis BD.
europepmc +1 more source
Australian Education Technologies Trends 2018
The Australian Educational Technologies Trends (AETT) report provides an overview to assist teachers, school leaders, academics and industry, in understanding and planning for the use of digital technologies in Australian schools over the next five years
Jones, M +15 more
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Public Search Behavior and Tuberculosis Cases in Indonesia 2019-2023: An Infodemiology Study Using Google Trends . [PDF]
Rahayu SR +11 more
europepmc +1 more source
Industry 4.0: state of the art and future trends
Lida Xu, E. Xu, Ling Li
semanticscholar +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
A global decline in atmospheric dust during the 21st century. [PDF]
Gupta AK +8 more
europepmc +1 more source

