Results 61 to 70 of about 91,292 (354)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Evaluation of a Treponema IgG ELISA alone and in combination with an IgM ELISA as substitutes for Treponema pallidum particle agglutination (TPPA) as confirmatory tests in a two-tier diagnostic algorithm for diagnosis of syphilis infection

Journal of Laboratory Medicine
The Treponema pallidum particle agglutination (TPPA) has been used for decades for serological diagnostics of syphilis but is no longer available. Therefore, we evaluated the Treponema IgG ELISA (TpG) alone and in combination with the Treponema IgM ELISA
Wellinghausen Nele, Rangel Vivar Teresa Esthela, Plonné Dietmar   +2 more
doaj   +1 more source

Genomic Insights Into the Treponema Genus: Taxonomic Resolution of Treponema vincentii and Description of Two Novel Species, Treponema plautii sp. nov. and Treponema sinense sp. nov. [PDF]

Mol Oral Microbiol
ABSTRACT Objectives Periodontal disease, a global health concern, is strongly associated with oral treponemes. However, the taxonomy of some species remains unresolved, hindering our understanding of their roles in disease. This study aims to clarify the taxonomy of three strains isolated from patients with periodontal disease using phylogenomic and ...
Fong JYH, Yeung ML, Li TT, Li WH, Ma Y, Zhao Y, Leung WK, Teng JLL.   +7 more
europepmc   +2 more sources

Time series model based on global structure of complete genome [PDF]

, 2000
A time series model based on the global structure of the complete genome is proposed. Three kinds of length sequences of the complete genome are considered. The correlation dimensions and Hurst exponents of the length sequences are calculated.
Allegrini, Buldyrev, Feder, Fraser, Grassberger, Grassberger, Grosberg, Herzel, Hurst, Lechner, Li, Lou, Luo, Luo, Mandelbrot, Peng, Pennisi, Provata, Stanley, Vo Anh, Voss, Voss, Zu-Guo Yu   +22 more
core   +3 more sources

Detection of specific Treponema species and Dichelobacter nodosus from digital dermatitis (Mortellaro's disease) lesions in Swiss cattle.

Schweizer Archiv für Tierheilkunde, 2019
INTRODUCTION The aim of this study was to determine the prevalence of the three Treponema species as well as D. nodosus in Digital dermatitis (DD) and slurry of Swiss cattle using PCR.
M. Alsaaod, I. Locher, Jörg Jores, Pauline Grimm, Isabelle Brodard, Adrian Steiner, Peter Kuhnert   +6 more
semanticscholar   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

Advanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena, Estelle Morvan, Clara Lambert, Anagha Kallisseri Parambil, Martin Lefeuvre, Zeren Xu, Nadia El Mammeri, Florian Malard, Erick J. Dufourc, Cécile Feuillie, Christophe Grangeasse, Birgit Habenstein   +11 more
wiley   +1 more source

Comparación entre pruebas treponémicas y no treponémicas para la detección de sífilis

Biomédica: revista del Instituto Nacional de Salud
Introducción. Tradicionalmente, la sífilis se ha detectado con pruebas no treponémicas y se ha confirmado con pruebas treponémicas, un algoritmo diagnóstico implementado a nivel mundial. Objetivo.
Verónica Aguaiza, Rosa F. Chiriboga-Ponce   +1 more
doaj   +1 more source

An Unusual Case of Tertiary Syphilis Behaving Like Tongue Squamous Cell Carcinoma. [PDF]

, 2018
Syphilis may present with a myriad of oral manifestations in the primary, secondary, and tertiary stages, and may be confused with malignancy. Despite a rise in the incidence of syphilis, tertiary syphilis is exceedingly rare.
Farwell, D Gregory, Kuhn, Brooks T, Solis, Roberto N   +2 more
core   +2 more sources

Native cellular architecture of Treponema denticola revealed by cryo-electron tomography [PDF]

, 2009
Using cryo-electron tomography, we are developing a refined description of native cellular structures in the pathogenic spirochete Treponema denticola. Tightly organized bundles of periplasmic flagella were readily observed in intact plunge-frozen cells.
Hsieh, Chyong-Ere, Izard, Jacques, Limberger, Ronald J., Mannella, Carmen A., Marko, Michael   +4 more
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source