Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis(1.). [PDF]
Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and ...
Cavassini, M. +11 more
core +3 more sources
Activation of the classical and alternative pathways of complement by Treponema pallidum subsp. pallidum and Treponema vincentii [PDF]
Both in vivo and in vitro studies have indicated that complement plays an important role in the syphilitic immune responses. Few quantitative data are available concerning activation of the classical pathway by Treponema pallidum subsp. pallidum, and no information is available on treponemal activation of the alternative pathway.
openaire +2 more sources
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal +7 more
wiley +1 more source
The “Great Masquerader" Strikes Again: Secondary Syphilis Presentation with Erythema Multiforme (EM)-Like Lesions [PDF]
Syphilis is a sexually transmitted disease known to present with highly variable manifestations, especially when left untreated. Patients who present to Internal Medicine Departments with fever and a rash are always a diagnostic challenge since mild ...
Brom, Adi +3 more
core +1 more source
SINGLE CELL INOCULATIONS WITH TREPONEMA PALLIDUM [PDF]
The injection of one or several Treponema pallidum into the testicles of rabbits does not induce syphilitic infection. A negative tissue transfer experiment does not preclude the presence of Treponema pallidum in the inoculum nor does it indicate the absence of syphilis in the source animal.
Hugh J. Morgan, Clarence S. Thomas
openaire +3 more sources
ABSTRACT Stillbirth is a public health challenge to low‐ and middle‐income countries, and the rate of stillbirths in Nepal is 15.7 per 1000 births. Stillbirths are reviewed under the maternal and perinatal death surveillance and response (MPDSR) system in Nepal, where the causes of deaths and preventive strategies should be identified, but there are ...
Nuwadatta Subedi +4 more
wiley +1 more source
A Case of Miller−Fisher Overlap Syndrome With Positive Anti‐GM4 Antibody and Atypical Symptoms
ABSTRACT Background Miller−Fisher syndrome (MFS) is a recognized clinical variant of Guillain−Barré syndrome (GBS), characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia. When accompanied by additional symptoms such as bulbar palsy, limb weakness, or lethargy, it is termed MFS overlap syndrome.
Miao Tang +9 more
wiley +1 more source
Tomographic reconstruction of treponemal cytoplasmic filaments reveals novel bridging and anchoring components [PDF]
An understanding of the involvement of bacterial cytoplasmic filaments in cell division requires the elucidation of the structural organization of those filamentous structures.
Barnard, Rita M. +5 more
core +1 more source
Adherence of Treponema pallidum subsp. pallidum in the Rabbit Placenta
Congenital syphilis is the consequence of transplacental passage of Treponema pallidum. A system was developed to deliver virulent T. pallidum, Nichols strain, through an isolated uterine horn of a pregnant rabbit in order to investigate the mechanism by which T. pallidum is able to cross the placenta.
Andrew W. O. Burgess +3 more
openaire +3 more sources
INTRODUCTION: Due to the existence of a variety of types of non-venereal syphilis caused by the related T. pallidum, regular serological testing such as Rapid Plasma Reagin (RPR) and Chemiluminescent Microparticle Immunoassay Technique (CMIA) are often ...
Abibou Simpore +12 more
doaj +1 more source

