Results 271 to 280 of about 63,007 (294)
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Autophagy promotes phagocytosis and clearance of Treponema pallidum via the NLRP3 inflammasome in macrophages

Journal of the European Academy of Dermatology and Venereology, 2020
Elucidating the mechanism of the macrophage phagocytic response will improve our knowledge of host defence against Treponema pallidum.
S. Xu   +7 more
semanticscholar   +1 more source

Molecular Subtyping of Treponema pallidum Subspecies pallidum

Sexually Transmitted Diseases, 1998
Epidemiologic studies on syphilis have been hampered by the fact that strains of Treponema pallidum subspecies pallidum (T. pallidum), the causative agent of this disease, cannot be differentiated by either protein-based or deoxyribonucleic acid-based methods. Syphilis is endemic in many developing countries and is common in some industrialized nations.
Cheng Y. Chen   +6 more
openaire   +3 more sources

Culture of Treponema pallidum

1994
Publisher Summary This chapter discusses the culture of Treponerna pallidum ( T. pallidum ). T. pallidum can be cultivated in a variety of tissue culture vessels; 24-, 12-, and 6-well culture plates, and 25-, 75-, and 150-cm 2 tissue culture flasks, have been used successfully to cultivate T. pallidum .
openaire   +3 more sources

Azithromycin resistance in Treponema pallidum

Current Opinion in Infectious Diseases, 2008
Although the recommended treatment for syphilis is penicillin, azithromycin has been used as an alternative. We discuss azithromycin-related treatment failures and resistance in Treponema pallidum, and propose ways to meet the resulting clinical and public health challenges.Azithromycin treatment failures in syphilis were first noted in San Francisco ...
Jeffrey D. Klausner, Kenneth A. Katz
openaire   +3 more sources

Treponema pallidum

2002
Publisher Summary Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted infection (STI), with diverse clinical manifestations that occur in distinct stages. Just as many emerging infectious diseases, syphilis is at first highly virulent, but over time it becomes a more chronic infection. Regardless of its origin,
openaire   +2 more sources

Pathogenesis and Immunology of Treponema Pallidum

Annual Review of Microbiology, 1981
THE DISEASE ....... ....... ......... .... ... ....... ... ... ... ...... .. 30 PATHOGENESIS ...... ......... ..... ... ........ ........ ...... .... 32 Mucopolysaccharides ... .. ...... 33 Cultured cell receptor ... ... ... 33 Treponemal capsule ..... ......... ...... ....... ......... ..... .. ... ..... ... ... . ..... ..... ..
openaire   +3 more sources

Perianal Treponema pallidum

Mayo Clinic Proceedings, 2023
Mark, Hopkins   +2 more
openaire   +2 more sources

Investigation of the immune escape mechanism of Treponema pallidum

Infection, 2022
Yun-An Tang   +11 more
semanticscholar   +1 more source

Recombinant Treponema pallidum protein Tp47 induces angiogenesis by modulating the matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in endothelial cells

Journal of the European Academy of Dermatology and Venereology, 2019
Although angiogenesis is an obvious pathological manifestation in the pathogenesis of syphilis, little is known about the underlying mechanisms of angiogenesis induced by reactions to Treponema pallidum antigens.
Zheng-Xiang Gao   +5 more
semanticscholar   +1 more source

Molecular biology of Treponema pallidum

1992
The spirochaete Treponema pallidum subsp. pallidum, the causative agent of the venereal disease syphilis, has been the subject of extensive studies ever since its discovery over eighty years ago. The study of this pathogen has been hampered by inability to cultivate the pathogenic treponemes in vitro. The last decade a number of investigators have used
openaire   +3 more sources

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