Results 51 to 60 of about 9,269 (165)

Lessons From Astaxanthin Therapy to Combat Oral Premalignant and Malignant Lesions: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Oral cancer is one of the most common head and neck malignancies and remains associated with high morbidity, mortality, and treatment‐related toxicity. Despite advances in surgery, radiotherapy, and chemotherapy, there is still a need for safer adjunctive therapies with better therapeutic potential.
Reza Arefnezhad   +12 more
wiley   +1 more source

Comparison of efficacy and tolerability of tretinoin gel 0.05% with adapalene gel 0.1% in treating mild to moderate acne vulgaris

open access: yesFiyz̤, 2018
Background: Acne vulgaris is an inflammatory skin disease. Topical retinoids with significant anti-inflammatory properties are used for treatment of acne. The common side effect of topical retinoids is local irritation.
Akram Ansar   +4 more
doaj  

Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1162-1172, July 2026.
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast   +22 more
wiley   +1 more source

Gene expression regulation by retinoic acid

open access: yesJournal of Lipid Research, 2002
Over the last quarter century, more than 532 genes have been put forward as regulatory targets of retinoic acid. In some cases this control is direct, driven by a liganded heterodimer of retinoid receptors bound to a DNA response element; in others, it ...
James E. Balmer, Rune Blomhoff
doaj   +1 more source

Targeted Topical Delivery of Retinoids in the Management of Acne Vulgaris: Current Formulations and Novel Delivery Systems

open access: yesPharmaceutics, 2019
Acne vulgaris is a common inflammatory pilosebaceous condition that affects 80−90% of adolescents. Since the introduction of tretinoin over 40 years ago, topical retinoid products have been a mainstay of acne treatment.
Gemma Latter   +4 more
doaj   +1 more source

A Pilot Trial of Pioglitazone HCl and Tretinoin in ALS: Cerebrospinal Fluid Biomarkers to Monitor Drug Efficacy and Predict Rate of Disease Progression

open access: yesNeurology Research International, 2012
Objectives. To determine if therapy with pioglitazone HCl and tretinoin could slow disease progression in patients with ALS. Levels of tau and pNFH in the cerebrospinal fluid were measured to see if they could serve as prognostic indicators. Methods.
Todd D. Levine   +6 more
doaj   +1 more source

A Double Blind Immunohistological Study Of The Effect Of Topical Tretinoin On Photoaged Skin

open access: yesIndian Journal of Dermatology, 1998
Fifteen very fair women with mild to moderate photoaging in there 60’s were tested by doubled blind immunohistological study. Tretinoin 0.05% cream applied daily was compared to its vehicle with regards to epidermal, basal, spinous
Bose Sumit Kumar
doaj  

Evaluation of the efficacy of 50% citric acid solution in plane wart treatment

open access: yesIndian Journal of Dermatology, 2007
Background and Aims: Treatment of plane warts is problematic, methods such as cryotherapy and cauterization is associated with high recurrence rate, risk of scar, pain and high cost.
Vali Anahita, Ferdowsi Faezeh
doaj  

Topical retinoids and risk of major congenital malformations and spontaneous abortion: a systematic review and meta-analysis

open access: yesFrontiers in Drug Safety and Regulation
BackgroundTopical retinoids are commonly prescribed for dermatological conditions during reproductive years; however, concerns regarding teratogenicity have persisted due to the established risks associated with oral retinoids. This systematic review and
Alaa Baqer Alali   +9 more
doaj   +1 more source

A Comparative Study of the Efficacy of Platelet-rich Plasma Therapy versus Topical Application of 0.1% Tretinoin Gel in the Management of Striae Gravidarum

open access: yesJournal of Marine Medical Society
Aim: To determine the relative efficacy of platelet rich plasma therapy versus topical 0.1% tretinoin gel in the management of striae gravidarum. Objectives: To determine the degree of response to platelet rich plasma therapy in comparison with topical 0.
Reetu Agarwal   +4 more
doaj   +1 more source

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