Results 51 to 60 of about 254 (146)
Recruitment of the human TREX complex to mRNA during splicing [PDF]
Genes & Development, 2005 In yeast, the TREX complex contains the THO transcription elongation complex, which functions in direct cotranscriptional recruitment of the mRNA export proteins Sub2 and Yra1 to nascent transcripts. Here we report the identification of the human THO complex and show that it associates with spliced mRNA, but not with unspliced pre-mRNA in vitro ...
Seiji, Masuda +5 more
openaire +2 more sources
Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá +4 more
wiley +1 more source
Journal of the Royal Anthropological Institute, EarlyView.The year 2025 marked the ninetieth since a fossil hominin occipital bone was discovered in Swanscombe, southeast England. In subsequent years, its parietal bones were found, producing what remains the oldest partial cranium from Britain today. In the earliest analyses, it was interpreted as a descendant of the infamous fraudulent fossil Piltdown Man ...
Emma E. Bird, Chris Stringer
wiley +1 more source
The THO/TREX complex functions in disease resistance in Arabidopsis [PDF]
Plant Signaling & Behavior, 2012 Powdery mildew pathogens are biotrophic fungi that infect large number of plant species. EDR1 (ENHANCED DISEASE RESISTANCE 1) is a negative regulator of plant disease resistance, and loss-of-function in the EDR1 gene confers enhanced disease resistance to powdery mildew pathogen Golovinomyces cichoracearum.
Huairong, Pan +2 more
openaire +2 more sources
Cutting freedom down to size Liberté calibrée
Journal of the Royal Anthropological Institute, EarlyView.Freedom, as a concept and a value, presents limited prospects for anthropological comparison. The study of enslavement, much neglected in attempts to develop an anthropology of freedom, shows that freedom has been imagined by the enslaved as the opposite of their condition only under particular circumstances.
Harri Englund
wiley +1 more source
Türk Oftalmoloji Dergisi, 2019 Objectives:To assess outcomes of a risk-based algorithm-guided treatment protocol for neovascular age-related macular degeneration.Materials and Methods:Two hundred and ten eyes of 184 patients managed with anti-vascular endothelial growth factor (anti ...
Murat Karaçorlu +4 more
doaj +1 more source
Introduction: On the fickleness of friendship Introduction : de l'inconstance en amitié
Journal of the Royal Anthropological Institute, EarlyView.In this Introduction to the special section, I provide a brief overview of the anthropology of friendship, particularly from the 1960s to the present, before focusing on the four articles that form the main body of the section. I argue that anthropologists who do not regard themselves as specialists in friendship will still find much to gain from ...
Simon Coleman
wiley +1 more source
TReX: Tokenizer Regression for Optimal Data Mixture
Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 1: Long Papers)Accepted to EACL 2026. Long Paper. (19 languages studied: Chinese, Greek, Japanese, etc.)
Inho Won +5 more
openaire +3 more sources
Chtop is a component of the dynamic TREX mRNA export complex [PDF]
The EMBO Journal, 2013 The TREX complex couples nuclear pre-mRNA processing with mRNA export and contains multiple protein components, including Uap56, Alyref, Cip29 and the multi-subunit THO complex. Here, we have identified Chtop as a novel TREX component. We show that both Chtop and Alyref activate the ATPase and RNA helicase activities of Uap56 and that Uap56 functions ...
Chang, CT +6 more
openaire +3 more sources
Accounting Perspectives, EarlyView.ABSTRACT Accountants must master a considerable body of highly complex knowledge to attain the level of professional proficiency required to comply with accounting standards and uphold their public responsibility. Postsecondary education and professional certification bodies provide only a portion of the technical knowledge that accountants need to ...
Leslie Berger +2 more
wiley +1 more source