Results 31 to 40 of about 278,419 (266)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Achievement of Sustained Net Plasma Heating in a Fusion Experiment with the Optometrist Algorithm

open access: yesScientific Reports, 2017
Many fields of basic and applied science require efficiently exploring complex systems with high dimensionality. An example of such a challenge is optimising the performance of plasma fusion experiments.
E. A. Baltz   +7 more
doaj   +1 more source

Effective Radiotherapy Cured Cauda Equina Syndrome Caused by Remitted Intracranial Germinoma Depositing

open access: yesPediatrics and Neonatology, 2012
Cauda equina syndrome (CES) in children is very rare and can permanently disable. A remitted intracranial germinoma depositing on the spinal cord, leading to CES, has never been reported.
Ying-Chun Lu   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

INCREASING KNOWLEDGE OF MIDWIFERY STUDENTS ABOUT FLOOD DISASTERS USING THE JIGSAW LEARNING METHOD

open access: yesNurse and Health
Background: Not having had direct experience in dealing with disasters means that students are not ready to be prepared, so disaster education using a jigsaw learning method is needed. Objectives:  This research aims to study the effect of the jigsaw
Mika Oktarina   +4 more
doaj   +1 more source

Heuristic Understanding as a Component of Collaborative, Interdisciplinary, Social Justice Advocacy Research

open access: yesJournal for Social Action in Counseling and Psychology, 2012
This article describes the experiences of three university colleagues with a common interest in, and commitment to, the retention of students from traditionally underserved populations including those who are racial/ethnic minorities or first-generation ...
Stephanie Bauman   +2 more
doaj   +1 more source

Antibiogram of Salmonella spp Isolates from Raw Chicken Meat of Kathmandu Valley

open access: yesNepal Journal of Biotechnology, 2023
Salmonella is one of the pathogenic microbe responsible in food borne diseases. In developing countries like Nepal,  Salmonellosis is one of the leading food-borne disease.
Abhimat Subedi   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Uncommon suffix tries

open access: yesRandom Structures & Algorithms, 2013
AbstractCommon assumptions on the source producing the words inserted in a suffix trie with n leaves lead to a height and saturation level. We provide an example of a suffix trie whose height increases faster than a power of n and another one whose saturation level is negligible with respect to . Both are built from VLMC (Variable Length Markov Chain)
Cénac, Peggy   +3 more
openaire   +6 more sources

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